Isolation of discrete nanoparticle -: DNA conjugates for plasmonic applications

被引：154
作者：
Claridge, Shelley A. [1 ,2 ]
Liang, Huiyang W. [1 ,2 ]
Basu, S. Roger [1 ,2 ]
Frechet, Jean M. J. [1 ,2 ]
Alivisatos, A. Paul [1 ,2 ]
机构：
[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
[2] EO Lawrence Berkeley Natl Lab, Div Mat Sci, Berkeley, CA 94720 USA
来源：
NANO LETTERS | 2008年 / 8卷 / 04期
关键词：
D O I：
10.1021/nl0802032
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Discrete DNA-gold nanoparticle conjugates with DNA lengths as short as 15 bases for both 5 and 20 nm gold particles have been purified by anion-exchange HPLC. Conjugates comprising short DNA (<40 bases) and large gold particles (>= 20 nm) are difficult to purify by other means and are potential substrates for plasmon coupling experiments. Conjugate purity is demonstrated by hybridizing complementary conjugates to form discrete structures, which are visualized by TEM.
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页码：1202 / 1206
页数：5
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