Muscarine, imidazole, oxazole, and thiazole alkaloids

被引：219
作者：
Jin, Zhong [1 ,2 ]
机构：
[1] Nankai Univ, State Key Lab, Tianjin 30001, Peoples R China
[2] Nankai Univ, Inst Elementoorgan Chem, Tianjin 30001, Peoples R China
来源：
NATURAL PRODUCT REPORTS | 2011年 / 28卷 / 06期
关键词：
CONCISE TOTAL-SYNTHESIS; MARINE NATURAL-PRODUCTS; ASYMMETRIC TOTAL-SYNTHESIS; SULFATED SESTERTERPENE ALKALOIDS; STREPTOTHRICIN CLASS ANTIBIOTICS; ENANTIOSELECTIVE TOTAL-SYNTHESIS; DIMERIC BROMOPYRROLE ALKALOIDS; HISTONE DEACETYLASE INHIBITOR; SECRETION SYSTEM INHIBITORS; PUMMERER REACTION CHEMISTRY;
D O I：
10.1039/c0np00074d
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A great number of structurally diverse natural products containing five-membered heterocyclic subunits, such as imidazole, oxazole, thiazole, and their saturated congeners, are abundant in nature. These naturally occurring metabolites often exhibit extensive and pharmacologically important biological activities. The latest progress in the isolation, biological activities, chemical synthetic studies, and biosynthetic pathways on these natural products is summarized in this review.
引用
收藏
页码：1143 / 1191
页数：49
相关论文
共 469 条
[91]   A concise and efficient synthesis of (-)-allosamizoline [J].
Donohoe, Timothy J. ;
Rosa, Carla P. .
ORGANIC LETTERS, 2007, 9 (26) :5509-5511
[92]   Alkaloids from a deep ocean sediment-derived fungus Penicillium sp and their antitumor activities [J].
Du, Lin ;
Feng, Teng ;
Zhao, Boyu ;
Li, Dehai ;
Cai, Shengxin ;
Zhu, Tianjiao ;
Wang, Fengping ;
Xiao, Xiang ;
Gu, Qianqun .
JOURNAL OF ANTIBIOTICS, 2010, 63 (04) :165-170
[93]   New alkaloids and diterpenes from a deep ocean sediment derived fungus Penicillium sp. [J].
Du, Lin ;
Li, Dehai ;
Zhu, Tianjiao ;
Cai, Shengxin ;
Wang, Fengping ;
Xiao, Xiang ;
Gu, Qianqun .
TETRAHEDRON, 2009, 65 (05) :1033-1039
[94]   Latrunculin A and its C-17-O-carbamates inhibit prostate tumor cell invasion and HIF-1 activation in breast tumor cells [J].
El Sayed, Khalid A. ;
Khanfar, Mohammad A. ;
Shallal, Hassan M. ;
Muralidharan, A. ;
Awate, Bhushan ;
Youssef, Diaa T. A. ;
Liu, Yang ;
Zhoo, Yu-Dong ;
Nagle, Dale G. ;
Shah, Girish .
JOURNAL OF NATURAL PRODUCTS, 2008, 71 (03) :396-402
[95]   Concise microwave-assisted synthesis of 2-aminoimidazole marine sponge alkaloids of the isonaamines series [J].
Ermolat'ev, D. S. ;
Alifanov, V. L. ;
Rybakov, V. B. ;
Babaev, E. V. ;
Van der Eycken, E. V. .
SYNTHESIS-STUTTGART, 2008, 13 (13) :2083-2088
[96]   A sequential two-component etherification/oxa-conjugate addition reaction: Asymmetric synthesis of (+)-leucascandrolide A macrolactone [J].
Evans, P. Andrew ;
Andrews, William J. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (29) :5426-5429
[97]   Calyculins and Related Marine Natural Products as Serine-Threonine Protein Phosphatase PP1 and PP2A Inhibitors and Total Syntheses of Calyculin A, B, and C [J].
Fagerholm, Annika E. ;
Habrant, Damien ;
Koskinen, Ari M. P. .
MARINE DRUGS, 2010, 8 (01) :122-172
[98]   A facile synthesis of (S)-gizzerosine, a potent agonist of the histamine H2-receptor [J].
Fanning, Kate N. ;
Sutherland, Andrew .
TETRAHEDRON LETTERS, 2007, 48 (48) :8479-8481
[99]   Lobozoanthamine, a new zoanthamine-type alkaloid from the Indonesian soft coral Lobophytum sp. [J].
Fattorusso, Ernesto ;
Romano, Adriana ;
Taglialatela-Scafati, Orazio ;
Achmad, M. Janib ;
Bavestrello, Giorgio ;
Cerrano, Carlo .
TETRAHEDRON LETTERS, 2008, 49 (14) :2189-2192
[100]   Extending Pummerer Reaction Chemistry. Application to the Total Synthesis of (±)-Dibromoagelaspongin [J].
Feldman, Ken S. ;
Fodor, Matthew D. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (45) :14964-+
567891011121314