Muscarine, imidazole, oxazole, and thiazole alkaloids

被引:219
作者
Jin, Zhong [1 ,2 ]
机构
[1] Nankai Univ, State Key Lab, Tianjin 30001, Peoples R China
[2] Nankai Univ, Inst Elementoorgan Chem, Tianjin 30001, Peoples R China
关键词
CONCISE TOTAL-SYNTHESIS; MARINE NATURAL-PRODUCTS; ASYMMETRIC TOTAL-SYNTHESIS; SULFATED SESTERTERPENE ALKALOIDS; STREPTOTHRICIN CLASS ANTIBIOTICS; ENANTIOSELECTIVE TOTAL-SYNTHESIS; DIMERIC BROMOPYRROLE ALKALOIDS; HISTONE DEACETYLASE INHIBITOR; SECRETION SYSTEM INHIBITORS; PUMMERER REACTION CHEMISTRY;
D O I
10.1039/c0np00074d
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A great number of structurally diverse natural products containing five-membered heterocyclic subunits, such as imidazole, oxazole, thiazole, and their saturated congeners, are abundant in nature. These naturally occurring metabolites often exhibit extensive and pharmacologically important biological activities. The latest progress in the isolation, biological activities, chemical synthetic studies, and biosynthetic pathways on these natural products is summarized in this review.
引用
收藏
页码:1143 / 1191
页数:49
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