A fast-responsed fluorescent probe for the selective detection hydrogen sulfide and tert- butoxy radical

被引:6
作者
Dong, Junyang [1 ,4 ]
Hu, Jianfeng [1 ,2 ]
Zhang, Hao [1 ,2 ,3 ]
机构
[1] Inner Mongolia Univ, Coll Chem & Chem Engn, Hohhot 010021, Peoples R China
[2] Inner Mongolia Key Lab Fine Organ Synth, Hohhot 010021, Peoples R China
[3] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China
[4] Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China
基金
中国国家自然科学基金;
关键词
Carbazole; Hydrogen sulfide; Tert-butoxy radical; Colorimetric probe; Cell imaging; LUMINESCENT PROBES; H2S;
D O I
10.1016/j.tet.2020.131317
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The fluorescent probe (1) for detecting hydrogen sulfide and tert-butoxy radical in aqueous environment and living cells was first developed. The probe 1 displayed excellent optical properties such as good selectivity, low detection limit (21 nM), quantitative detection (1-10 mu M), and very fast response times (<50 s) for monitor of hydrogen sulfide in aqueous environment. Furthermore, the color of the probe 1 solution changed from yellow to colorless when hydrogen sulfide added. More importantly, the probe 1 is successfully used to real-time imaging for hydrogen sulfide and tert-butoxy radical in Hela cells. These merits play a significant role in the process for hydrogen sulfide detection considering the rapid metabolism in organisms. (C) 2020 Elsevier Ltd. All rights reserved.
引用
收藏
页数:6
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