Bicuspid Aortic Valve Stenosis: From Pathophysiological Mechanism, Imaging Diagnosis, to Clinical Treatment Methods

被引：4
作者：
Perrin, Nils [1 ,2 ]
Ibrahim, Reda [1 ]
Durrleman, Nicolas [1 ]
Basmadjian, Arsene [1 ]
Leroux, Lionel [3 ]
Demers, Philippe [1 ]
Modine, Thomas [3 ]
Ben Ali, Walid [1 ]
机构：
[1] Montreal Heart Inst, Struct Heart Intervent Program, Montreal, PQ, Canada
[2] Geneva Univ Hosp, Cardiol Div, Geneva, Switzerland
[3] CHU Bordeaux, Hop Cardiol Haut Leveque, Valvulopathies Chirurgie Cardiaque Cardiol Interv, Serv Med Chirurg, Bordeaux, France
来源：
FRONTIERS IN CARDIOVASCULAR MEDICINE | 2022年 / 8卷
基金：
瑞士国家科学基金会;
关键词：
bicuspid aortic valve stenosis bicuspid aortic valve; nomenclature; transcatheter aortic valve implantation; sizing approaches; review; COMPUTED-TOMOGRAPHY; TRANSCATHETER; REPLACEMENT; OUTCOMES; IMPLANTATION; DISEASE; CLASSIFICATION; RISK; TAVI; PREDICTORS;
D O I：
10.3389/fcvm.2021.798949
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Bicuspid aortic valve (BAV) is the most frequent congenital anomaly and has a natural evolution toward aortic regurgitation or stenosis due to the asymmetrical valve function associated with an evolutive ascending aortopathy. Several BAV classifications exist describing the presence and number of raphe, amount and location of calcium, and the symmetry of the functional cusps. The impact of BAV morphology on transcatheter aortic valve implantation (TAVI) outcomes still remains little investigated. Pivotal randomized trials comparing TAVI with surgery have excluded BAV until yet. However, data from registries and observational studies including highly selected patients have shown promising results of TAVI in BAV. With this review, we aimed at describing anatomical and pathophysiological characteristics of BAV, discussing the main aspects to assess diagnostic imaging modalities, and giving an overview of TAVI outcomes and technical considerations specific to BAV morphology.
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页数：11
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