The effect of a cardiopulmonary bypass system with biocompatible coating on fibrinogen levels determined by the TEG - functional fibrinogen method: preliminary results

被引：6

作者：

Fluger, I. ^{[2
]}

Maderova, K. ^{[2
]}

Simek, M. ^{[2
]}

Hajek, R. ^{[2
]}

Zapletalova, J. ^{[1
]}

Lonsky, V. ^{[2
]}

机构：

[1] Palacky Univ, Fac Med & Dent, Dept Biomed & Stat, CR-77147 Olomouc, Czech Republic

[2] Univ Hosp Olomouc, Dept Cardiac Surg, Olomouc, Czech Republic

来源：

PERFUSION-UK | 2011年 / 26卷 / 06期

关键词：

biocompatible surface; functional fibrinogen; TEG; coagulation; cardiopulmonary bypass; THROMBIN FORMATION; CIRCUITS; ACTIVATION;

D O I：

10.1177/0267659111415891

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

When cardiopulmonary bypass (CPB) is used, the blood comes into contact with foreign surfaces. To diminish this impact, various types of biocompatibly coated surfaces have been developed. The study assessed the effects of heparin-coated CPB systems on the level and function of fibrinogen as measured by thromboelastography (TEG), as compared with non-coated systems. No statistically significant differences between both groups were revealed by comparing paired data. In our study, heparin-coated CPB circuits had no significant effect on either fibrinogen level or its function.

引用

页码：503 / 509

页数：7