Repair of full-thickness defects in rabbit articular cartilage using bFGF and hyaluronan sponge

被引：0
作者：
Yamazaki, T
Tamura, J
Nakamura, T
Tabata, Y
Matsusue, Y
机构：
[1] Kyoto Univ, Dept Orthoped Surg, Sakyo Ku, Kyoto 6068507, Japan
[2] Kyoto Univ, Inst Frontier Med Sci, Sakyo Ku, Kyoto 6068507, Japan
[3] Shiga Univ Med Sci, Dept Orthoped Surg, Otsu, Shiga 5202192, Japan
来源：
BIOCERAMICS, VOL 16 | 2004年 / 254-2卷
关键词：
growth factor; carrier; drug delivery system;
D O I：
10.4028/www.scientific.net/KEM.254-256.1099
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Basic fibroblast growth factor (bFGF) is reported to be effective for cartilage repair, but its effects are limited without a drug delivery system because bFGF is lost by diffusion. We investigated the effects of exogenous basic fibroblast growth factor (bFGF) with drug delivery system on the repair of full-thickness cartilage defects. bFGF with gelatin microspheres and hyaluronan sponge improved the repair of osteochondral defects in rabbits.
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收藏
页码：1099 / 1102
页数：4
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