Acute Kidney Injury Definition and Diagnosis: A Narrative Review

被引:65
作者
Gameiro, Joana [1 ]
Fonseca, Jose Agapito [1 ]
Jorge, Sofia [1 ]
Lopes, Jose Antonio [1 ]
机构
[1] Ctr Hosp Lisboa Norte, Dept Med, Div Nephrol & Renal Transplantat, EPE, Av Prof Egas Moniz, P-1649035 Lisbon, Portugal
关键词
acute kidney injury; definition; incidence; classification; ACUTE-RENAL-FAILURE; CRITICALLY-ILL PATIENTS; GELATINASE-ASSOCIATED LIPOCALIN; INTENSIVE-CARE UNITS; CARDIAC-SURGERY; HOSPITALIZED-PATIENTS; CONSENSUS CONFERENCE; SERUM CREATININE; CARDIOTHORACIC SURGERY; KDIGO CLASSIFICATIONS;
D O I
10.3390/jcm7100307
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Acute kidney injury (AKI) is a complex syndrome characterized by a decrease in renal function and associated with numerous etiologies and pathophysiological mechanisms. It is a common diagnosis in hospitalized patients, with increasing incidence in recent decades, and associated with poorer short- and long-term outcomes and increased health care costs. Considering its impact on patient prognosis, research has focused on methods to assess patients at risk of developing AKI and diagnose subclinical AKI, as well as prevention and treatment strategies, for which an understanding of the epidemiology of AKI is crucial. In this review, we discuss the evolving definition and classification of AKI, and novel diagnostic methods.
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页数:13
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共 94 条
[21]   Current understanding and future directions in the application of TIMP-2 and IGFBP7 in AKI clinical practice [J].
Fan, Weixuan ;
Ankawi, Ghada ;
Zhang, Jingxiao ;
Digvijay, Kumar ;
Giavarina, Davide ;
Yin, Yongjie ;
Ronco, Claudio .
CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2019, 57 (05) :567-576
[22]   RCPE UK Consensus Conference Statement Management of acute kidney injury: the role of fluids, e-alerts and biomarkers [J].
Feehally, J. ;
Gilmore, I ;
Barasi, S. ;
Bosomworth, M. ;
Christie, B. ;
Davies, A. ;
Dhesi, J. ;
Dowdle, R. ;
Gibbins, C. ;
Gonzalez, I ;
Harding, S. ;
Lamont, D. ;
Murphy, G. ;
Ostermann, M. ;
Parr, J. ;
Stevens, P. E. .
JOURNAL OF THE ROYAL COLLEGE OF PHYSICIANS OF EDINBURGH, 2013, 43 (01) :37-38
[23]   INCIDENCE OF SEVERE ACUTE-RENAL-FAILURE IN ADULTS - RESULTS OF A COMMUNITY BASED STUDY [J].
FEEST, TG ;
ROUND, A ;
HAMAD, S .
BMJ-BRITISH MEDICAL JOURNAL, 1993, 306 (6876) :481-483
[24]   Validation of the Kidney Disease Improving Global Outcomes Criteria for AKI and Comparison of Three Criteria in Hospitalized Patients [J].
Fujii, Tomoko ;
Uchino, Shigehiko ;
Takinami, Masanori ;
Bellomo, Rinaldo .
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2014, 9 (05) :848-854
[25]   Acute kidney injury in major abdominal surgery: incidence, risk factors, pathogenesis and outcomes [J].
Gameiro, Joana ;
Fonseca, Jose Agapito ;
Neves, Marta ;
Jorge, Sofia ;
Lopes, Jose Antonio .
ANNALS OF INTENSIVE CARE, 2018, 8
[26]   A UNIFIED THEORY OF SEPSIS- INDUCED ACUTE KIDNEY INJURY: INFLAMMATION, MICROCIRCULATORY DYSFUNCTION, BIOENERGETICS, AND THE TUBULAR CELL ADAPTATION TO INJURY [J].
Gomez, Hernando ;
Ince, Can ;
De Backer, Daniel ;
Pickkers, Peter ;
Payen, Didier ;
Hotchkiss, John ;
Kellum, John A. .
SHOCK, 2014, 41 (01) :3-11
[27]   Acute Kidney Injury After Major Surgery: A Retrospective Analysis of Veterans Health Administration Data [J].
Grams, Morgan E. ;
Sang, Yingying ;
Coresh, Josef ;
Ballew, Shoshana ;
Matsushita, Kunihiro ;
Molnar, Miklos Z. ;
Szabo, Zoltan ;
Kalantar-Zadeh, Kamyar ;
Kovesdy, Csaba P. .
AMERICAN JOURNAL OF KIDNEY DISEASES, 2016, 67 (06) :872-880
[28]   IL-18 and Urinary NGAL Predict Dialysis and Graft Recovery after Kidney Transplantation [J].
Hall, Isaac E. ;
Yarlagadda, Sri G. ;
Coca, Steven G. ;
Wang, Zhu ;
Doshi, Mona ;
Devarajan, Prasad ;
Han, Won K. ;
Marcus, Richard J. ;
Parikh, Chirag R. .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2010, 21 (01) :189-197
[29]   Kidney Injury Molecule-1 (KIM-1): A novel biomarker for human renal proximal tubule injury [J].
Han, WK ;
Bailly, V ;
Abichandani, R ;
Thadhani, R ;
Bonventre, JV .
KIDNEY INTERNATIONAL, 2002, 62 (01) :237-244
[30]   RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis [J].
Hoste, Eric A. J. ;
Clermont, Gilles ;
Kersten, Alexander ;
Venkataraman, Ramesh ;
Angus, Derek C. ;
De Bacquer, Dirk ;
Kellum, John A. .
CRITICAL CARE, 2006, 10 (03)