Recent Advances in Type-2-Cell-Mediated Immunity: Insights from Helminth Infection

被引：158

作者：

Harris, Nicola L. ^{[1
]}

Loke, P'ng ^{[2
]}

机构：

[1] Ecole Polytech Fed Lausanne, Global Hlth Inst, CH-1015 Lausanne, Switzerland

[2] NYU, Sch Med, Dept Microbiol, New York, NY 10016 USA

来源：

IMMUNITY | 2017年 / 47卷 / 06期

基金：

欧洲研究理事会; 美国国家卫生研究院;

关键词：

INNATE LYMPHOID-CELLS; ALTERNATIVELY ACTIVATED MACROPHAGES; TISSUE-RESIDENT MACROPHAGES; TYPE-2; IMMUNITY; MAST-CELLS; TRICHINELLA-SPIRALIS; PROTECTIVE IMMUNITY; LUNG INFLAMMATION; IL-13; PRODUCTION; DENDRITIC CELLS;

D O I：

10.1016/j.immuni.2017.11.015

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Type-2-cell-mediated immune responses play a critical role in mediating both host-resistance and disease-tolerance mechanisms during helminth infections. Recently, type 2 cell responses have emerged as major regulators of tissue repair and metabolic homeostasis even under steady-state conditions. In this review, we consider how studies of helminth infection have contributed toward our expanding cellular and molecular understanding of type-2-cell-mediated immunity, as well as new areas such as the microbiome. By studying how these successful parasites form chronic infections without overt pathology, we are gaining additional insights into allergic and inflammatory diseases, as well as normal physiology.

引用

页码：1024 / 1036

页数：13

共 153 条

[51] Type 2 Innate Signals Stimulate Fibro/Adipogenic Progenitors to Facilitate Muscle Regeneration [J].

Heredia, Jose E. ;

Mukundan, Lata ;

Chen, Francis M. ;

Mueller, Alisa A. ;

Deo, Rahul C. ;

Locksley, Richard M. ;

Rando, Thomas A. ;

Chawla, Ajay .

CELL, 2013, 153 (02) :376-388

[52] Concerted Activity of IgG1 Antibodies and IL-4/IL-25-Dependent Effector Cells Trap Helminth Larvae in the Tissues following Vaccination with Defined Secreted Antigens, Providing Sterile Immunity to Challenge Infection [J].

Hewitson, James P. ;

Filbey, Kara J. ;

Bieren, Julia Esser-von ;

Camberis, Mali ;

Schwartz, Christian ;

Murray, Janice ;

Reynolds, Lisa A. ;

Blair, Natalie ;

Robertson, Elaine ;

Harcus, Yvonne ;

Boon, Louis ;

Huang, Stanley Ching-Cheng ;

Yang, Lihua ;

Tu, Yizheng ;

Miller, Mark J. ;

Voehringer, David ;

Le Gros, Graham ;

Harris, Nicola ;

Maizels, Rick M. .

PLOS PATHOGENS, 2015, 11 (03) :1-22

[53] Vaccination against helminth parasite infections [J].

Hewitson, James P. ;

Maizels, Rick M. .

EXPERT REVIEW OF VACCINES, 2014, 13 (04) :473-487

[54] IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcεRI signals [J].

Ho, Lien H. ;

Ohno, Tatsukuni ;

Oboki, Keisuke ;

Kajiwara, Naoki ;

Suto, Hajime ;

Iikura, Motoyasu ;

Okayama, Yoshimichi ;

Akira, Shizuo ;

Saito, Hirohisa ;

Galli, Stephen J. ;

Nakae, Susumu .

JOURNAL OF LEUKOCYTE BIOLOGY, 2007, 82 (06) :1481-1490

[55] Helminth infections: the great neglected tropical diseases [J].

Hotez, Peter J. ;

Brindley, Paul J. ;

Bethony, Jeffrey M. ;

King, Charles H. ;

Pearce, Edward J. ;

Jacobson, Julie .

JOURNAL OF CLINICAL INVESTIGATION, 2008, 118 (04) :1311-1321

[56] Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut [J].

Howitt, Michael R. ;

Lavoie, Sydney ;

Michaud, Monia ;

Blum, Arthur M. ;

Tran, Sara V. ;

Weinstock, Joel V. ;

Gallini, Carey Ann ;

Redding, Kevin ;

Margolskee, Robert F. ;

Osborne, Lisa C. ;

Artis, David ;

Garrett, Wendy S. .

SCIENCE, 2016, 351 (6279) :1329-1333

[57] Eosinophils and IL-4 Support Nematode Growth Coincident with an Innate Response to Tissue Injury [J].

Huang, Lu ;

Beiting, Daniel P. ;

Gebreselassie, Nebiat G. ;

Gagliardo, Lucille F. ;

Ruyechan, Maura C. ;

Lee, Nancy A. ;

Lee, James J. ;

Appleton, Judith A. .

PLOS PATHOGENS, 2015, 11 (12)

[58] Eosinophils Mediate Protective Immunity against Secondary Nematode Infection [J].

Huang, Lu ;

Gebreselassie, Nebiat G. ;

Gagliardo, Lucille F. ;

Ruyechan, Maura C. ;

Luber, Kierstin L. ;

Lee, Nancy A. ;

Lee, James J. ;

Appleton, Judith A. .

JOURNAL OF IMMUNOLOGY, 2015, 194 (01) :283-290

[59] Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages [J].

Huang, Stanley Ching-Cheng ;

Everts, Bart ;

Ivanova, Yulia ;

O'Sullivan, David ;

Nascimento, Marcia ;

Smith, Amber M. ;

Beatty, Wandy ;

Love-Gregory, Latisha ;

Lam, Wing Y. ;

O'Neil, Christina M. ;

Yan, Cong ;

Du, Hong ;

Abumrad, Nada A. ;

Urban, Joseph F., Jr. ;

Artyomov, Maxim N. ;

Pearce, Erika L. ;

Pearce, Edward J. .

NATURE IMMUNOLOGY, 2014, 15 (09) :846-855

[60] IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine [J].

Huber, Samuel ;

Gagliani, Nicola ;

Zenewicz, Lauren A. ;

Huber, Francis J. ;

Bosurgi, Lidia ;

Hu, Bo ;

Hedl, Matija ;

Zhang, Wei ;

O'Connor, William, Jr. ;

Murphy, Andrew J. ;

Valenzuela, David M. ;

Yancopoulos, George D. ;

Booth, Carmen J. ;

Cho, Judy H. ;

Ouyang, Wenjun ;

Abraham, Clara ;

Flavell, Richard A. .

NATURE, 2012, 491 (7423) :259-+

← 1 2 3 4 5 6 7 8 9 10 →