HECK-MIZOROKI REACTION OF 4-IODO-1H-PYRAZOLES

被引：9

作者：

Usami, Yoshihide ^{[1
]}

Ichikawa, Hayato ^{[1
]}

Harusawa, Shinya ^{[1
]}

机构：

[1] Osaka Univ Pharmaceut Sci, Lab Pharmaceut Organ Chem, Osaka 5691094, Japan

来源：

HETEROCYCLES | 2011年 / 83卷 / 04期

关键词：

4-Alkenyl-1H-pyrazole; Synthesis; Heck-Mizoroki Reaction; Palladium; Direct Functionalization; CROSS-COUPLING REACTION; PALLADIUM; HALIDES; ARYL;

D O I：

10.3987/COM-11-12146

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Heck-Mizoroki reaction of 1-protected-4-iodo-1H-pyrazoles with various kinds of alkenes was examined and found to yield 1-protected-4-alkenyl-1H-pyrazoles. P(OEt)(3) was a suitable ligand for the cross-coupling reaction, together with the trityl group that acted as an appropriate protecting group of 1H-pyrazole.

引用

收藏

页码：827 / 835

页数：9

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