Fluoroquinolones in Industrial Poultry Production, Bacterial Resistance and Food Residues: a Review

被引：51

作者：

Gouvea, R. ^{[1
]}

Dos, Santos F. F. ^{[1
]}

Aquino, M. H. C. de ^{[2
]}

Pereira, V. L. de A. ^{[2
]}

机构：

[1] Univ Fed Fluminense, Sch Vet Med, Post Grad Program Vet Med PhD, Vet Hyg & Technol Proc Anim Prod, BR-24220000 Niteroi, RJ, Brazil

[2] Univ Fed Fluminense, Sch Vet Med, Dept Vet Collect Hlth & Publ Hlth, BR-24220000 Niteroi, RJ, Brazil

来源：

BRAZILIAN JOURNAL OF POULTRY SCIENCE | 2015年 / 17卷 / 01期

关键词：

Fluoroquinolones; bacterial resistance; food residues; poultry products; QUINOLONE RESISTANCE; CAMPYLOBACTER-JEJUNI; LAYING HENS; PHARMACOKINETICS; EGGS; ANTIMICROBIALS; CIPROFLOXACIN; ENROFLOXACIN; HISTORY;

D O I：

10.1590/1516-635x17011-10

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Fluoroquinolones are antimicrobial agents frequently used in poultry production and in human medicine. The use of such substances must comply with safety criteria, including withdrawal periods, doses, and treatment duration, as their misuse and abuse may cause bacterial resistance and the presence of residues in edible tissues. Consequently, the consumption of animal products with fluoroquinolone residues may result in the transmission of resistant bacteria. In addition, if residues are beyond the acceptable levels, fluoroquinolone active metabolites are harmful to human health. This article presents a review on the use of antimicrobials of the fluoroquinolone class in poultry production, focusing on the development of bacterial resistance to these drugs and the presence of their residues in poultry products.

引用

页码：1 / 10

页数：10

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[1] Pharmacokinetics and residues of ciprofloxacin and its metabolites in broiler chickens [J].