Lissencephaly in a Pekingese

被引：4

作者：

Shimbo, Genya ^{[1
]}

Tagawa, Michihito ^{[1
]}

Oohashi, Eiji ^{[2
]}

Yanagawa, Masashi ^{[3
]}

Miyahara, Kazuro ^{[1
]}

机构：

[1] Obihiro Univ Agr & Vet Med, Vet Med Ctr, Obihiro, Hokkaido 0808555, Japan

[2] Akashiya Anim Clin, Makubetsu, Hokkaido 0890535, Japan

[3] Obihiro Univ Agr & Vet Med, Dept Appl Vet Med, Obihiro, Hokkaido 0808555, Japan

来源：

JOURNAL OF VETERINARY MEDICAL SCIENCE | 2017年 / 79卷 / 10期

关键词：

lissencephaly; magnetic resonance imaging; Pekingese; LHASA APSO DOGS; NEURONAL MIGRATION; CORTICAL DEVELOPMENT; ARACHNOID CYSTS; FEATURES; BRAIN;

D O I：

10.1292/jvms.17-0271

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

A 1-year-old neutered male Pekingese was presented for evaluation and further treatment of cluster seizures. The dog had behavioral abnormalities, and a prosencephalic lesion was suspected following neurological examination. The dog showed signs of learning difficulty. Magnetic resonance imaging of the brain revealed a remarkably smooth cerebral cortex with a reduced number of gyri, as well as a cystic lesion associated with the quadrigeminal cistern. A diagnosis of lissencephaly, concurrent with a quadrigeminal cisternal cyst, was made. High-dose and multiple anticonvulsants were necessary to control the seizures. This is the first report of lissencephaly in a Pekingese.

引用

页码：1694 / 1697

页数：4

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