Evidenced-Based Approaches to Support the Development of Endocrine-Mediated Adverse Outcome Pathways: Challenges and Opportunities

被引：6

作者：

Audouze, Karine ^{[1
]}

Zgheib, Elias ^{[1
]}

Abass, Khaled ^{[2
,3
]}

Baig, Asma H. ^{[4
]}

Forner-Piquer, Isabel ^{[4
]}

Holbech, Henrik ^{[5
]}

Knapen, Dries ^{[6
]}

Leonards, Pim E. G. ^{[7
]}

Lupu, Diana I. ^{[8
]}

Palaniswamy, Saranya ^{[9
]}

Rautio, Arja ^{[2
]}

Sapounidou, Maria ^{[10
]}

Martin, Olwenn V. ^{[4
]}

机构：

[1] Univ Paris, T3S, Inserm U1124, Paris, France

[2] Univ Oulu, Univ Arctic, Thule Inst, Oulu, Finland

[3] Menoufia Univ, Dept Pesticides, Menoufia, Egypt

[4] Brunel Univ London, Ctr Pollut Res & Policy, Uxbridge, England

[5] Univ Southern Denmark, Dept Biol, Odense, Denmark

[6] Univ Antwerp, Dept Vet Sci, Zebrafishlab, Antwerp, Belgium

[7] Vrije Univ Amsterdam, Dept Environm & Hlth, Amsterdam, Netherlands

[8] Uppsala Univ, Evolutionary Biol Ctr, Uppsala, Sweden

[9] Univ Oulu, Fac Med, Ctr Life Course Hlth Res, Oulu, Finland

[10] Umea Univ, Fac Sci & Technol, Dept Chem, Umea, Sweden

来源：

FRONTIERS IN TOXICOLOGY | 2021年 / 3卷

基金：

欧盟地平线“2020”;

关键词：

adverse outcome pathways; endocrine disruption; systematic (literature) review; machine learning; evidence-based methods; BRADFORD-HILL CONSIDERATIONS; SPECIES EXTRAPOLATION; FRAMEWORK; CHEMICALS; WEIGHT; MODELS; RISK;

D O I：

10.3389/ftox.2021.787017

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

引用

页数：10

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