SUBRETINAL TRANSPLANTATION OF AN AUTOLOGOUS RETINAL FREE FLAP FOR CHRONIC RETINAL DETACHMENT WITH PROLIFERATIVE VITREORETINOPATHY WITH AND WITHOUT MACULAR HOLE

被引:24
作者
Thomas, Akshay S. [1 ]
Mahmoud, Tamer H. [2 ]
机构
[1] Duke Univ, Sch Med, Dept Ophthalmol, Durham, NC USA
[2] Oakland Univ, William Beaumont Sch Med, Associated Retinal Consultants, Beaumont Neurosci Ctr Bldg,3555 W, Royal Oak, MI 48073 USA
来源
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | 2018年 / 38卷
关键词
macular hole; retinal detachment; retinal flap; retinal transplant; proliferative vitreoretinopathy; PIGMENT EPITHELIUM; DEGENERATION;
D O I
10.1097/IAE.0000000000002026
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To describe the surgical technique for subretinal transplantation of an autologous retinal free flap in cases of chronic retinal detachment with proliferative vitreoretinopathy with and without a macular hole. Methods: Descriptive case series. Results: Two patients with recurrent retinal detachment with proliferative vitreoretinopathy were referred for surgical evaluation. The first patient had high myopia and a macular hole. Acuity at the last time of sustained retinal reattachment was 20/400 for the first patient and counting fingers for the second patient and, in both cases, declined to light perception in the months after redetachment. Despite membrane/internal limiting membrane peeling, surgical repair required an inferior retinectomy in both cases. A retinal free flap was placed subfoveally. In the first patient, the flap was placed with the photoreceptors facing bare retinal pigment epithelium. In the second patient, the flap was inverted so its photoreceptors faced residual macular photoreceptors. The retina was flattened over the flap. Postoperatively, vision improved to 20/160 and 20/400 in the first and second patient respectively. Conclusion: Subretinal placement of a retinal flap is possible in eyes with retinal detachment and proliferative vitreoretinopathy with and without macular hole. Whether such a flap results in superior visual and anatomical outcomes remains to be seen.
引用
收藏
页码:S121 / S124
页数:4
相关论文
共 5 条
[1]   Outcome of transplantation of autologous retinal pigment epithelium in age-related macular degeneration: A prospective trial [J].
Binder, S ;
Krebs, I ;
Hilgers, RD ;
Abri, A ;
Stolba, U ;
Assadoulina, A ;
Kellner, L ;
Stanzel, BV ;
Jahn, C ;
Feichtinger, H .
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2004, 45 (11) :4151-4160
[2]   Proliferation of the ciliary epithelium with retinal neuronal and photoreceptor cell differentiation in human eyes with retinal detachment and proliferative vitreoretinopathy [J].
Ducournau, Yvette ;
Boscher, Claude ;
Adelman, Ron A. ;
Guillaubey, Colette ;
Schmidt-Morand, Didier ;
Mosnier, Jean-Francois ;
Ducournau, Didier .
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2012, 250 (03) :409-423
[3]   Autologous Neurosensory Retinal Free Flap for Closure of Refractory Myopic Macular Holes [J].
Grewal, Dilraj S. ;
Mahmoud, Tamer H. .
JAMA OPHTHALMOLOGY, 2016, 134 (02) :229-230
[4]   Autologous transplantation of the retinal pigment epithelium and choroid in the treatment of neovascular age-related macular degeneration [J].
MacLaren, Robert E. ;
Uppal, Gurmit S. ;
Balaggan, Kamaljit S. ;
Tufail, Adnan ;
Munro, Peter M. G. ;
Milliken, Andrew B. ;
Ali, Robin R. ;
Rubin, Gary S. ;
Aylward, G. William ;
da Cruz, Lyndon .
OPHTHALMOLOGY, 2007, 114 (03) :561-570
[5]   A Free Retinal Pigment Epithelium-Choroid Graft in Patients With Exudative Age-Related Macular Degeneration: Results up to 7 Years [J].
van Zeeburg, Elsbeth J. T. ;
Maaijwee, Kristel J. M. ;
Missotten, Tom O. A. R. ;
Heimann, Heinrich ;
van Meurs, Jan C. .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 2012, 153 (01) :120-127