Stem cell responses to nanotopography

被引：35

作者：

Park, Siyeon ^{[1
]}

Im, Gun-Il ^{[1
]}

机构：

[1] Dongguk Univ, Ilsan Hosp, Dept Orthopaed, Seoul, South Korea

来源：

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A | 2015年 / 103卷 / 03期

基金：

新加坡国家研究基金会;

关键词：

nanotopography; musculoskeletal regeneration; stem cells; OSTEOGENIC DIFFERENTIATION; CONTACT GUIDANCE; SURFACE NANOTOPOGRAPHY; NANOFIBROUS SCAFFOLDS; TITANIUM SURFACE; STROMAL CELLS; BEHAVIOR; TOPOGRAPHY; ADHESION; MORPHOLOGY;

D O I：

10.1002/jbm.a.35236

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Cells interact with various nanoscaled topographical and biochemical cues in their cellular macromolecular environment. Nanotopography recreates or mimic the cellular macromolecular environment in vitro. The influence of material surface topography on the behavior of adherent cells has been studied. Current techniques enable various kinds of nanopatterned surface to be generated and applied to cells. The purpose of this review is to provide an overview of nanotopography and its surface patterns, and introduce nanotopography effects on cell behavior including cell attachment, proliferation, and cell differentiation with particular emphasis on musculoskeletal regeneration. (c) 2014 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 103A: 1238-1245, 2015.

引用

页码：1238 / 1245

页数：8

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