PharmGKB summary: isoniazid pathway, pharmacokinetics

被引：42

作者：

Klein, Daniel J. ^{[1
,3
]}

Boukouvala, Sotiria ^{[4
]}

McDonagh, Ellen M. ^{[1
]}

Shuldiner, Scott R. ^{[1
]}

Laurieri, Nicola ^{[5
]}

Thorn, Caroline F. ^{[1
]}

Altman, Russ B. ^{[1
,2
]}

Klein, Teri E. ^{[1
]}

机构：

[1] Stanford Univ, Dept Genet, Stanford, CA 94305 USA

[2] Stanford Univ, Dept Bioengn, Stanford, CA 94305 USA

[3] Univ Southern Calif, Keck Sch Med, Los Angeles, CA USA

[4] Democritus Univ Thrace, Dept Mol Biol & Genet, Alexandroupolis, Greece

[5] Univ Oxford, Dept Pharmacol, Oxford, England

来源：

PHARMACOGENETICS AND GENOMICS | 2016年 / 26卷 / 09期

关键词：

anti-tuberculosis drug-induced hepatotoxicity; cytochrome P450 2E1; GSTT1; GSTM1; isoniazid; N-acetyltransferase; 2; pharmacokinetics; DRUG-INDUCED HEPATOTOXICITY; INDUCED LIVER-INJURY; N-ACETYLTRANSFERASE; S-TRANSFERASE M1; CYTOCHROME-P450; 2E1; GENOTYPE; GSTT1 GENETIC POLYMORPHISMS; SUSCEPTIBILITY RISK-FACTOR; HEPATIC BILE-ACIDS; ANTITUBERCULOSIS DRUGS; TUBERCULOSIS PATIENTS;

D O I：

10.1097/FPC.0000000000000232

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

[No abstract available]

引用

页码：436 / 444

页数：9

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