Mechanosensitive Channels: In Touch with Piezo

被引:51
|
作者
Xiao, Rui [1 ]
Xu, X. Z. Shawn
机构
[1] Univ Michigan, Inst Life Sci, Ann Arbor, MI 48109 USA
关键词
TRP CHANNELS; FAMILY;
D O I
10.1016/j.cub.2010.09.053
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Mechanosensory transduction underlies touch, hearing and proprioception and requires mechanosensitive channels that are directly gated by forces; however, the molecular identities of these channels remain largely elusive. A new study has identified Piezo1 and Piezo2 as a novel class of mechanosensitive channels.
引用
收藏
页码:R936 / R938
页数:3
相关论文
共 50 条
  • [31] Do mechanosensitive Piezo channels set in motion cell volume regulation?
    Mongin, Alexander A.
    PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2024, 476 (07): : 1019 - 1021
  • [32] Forces Bless You: Mechanosensitive Piezo Channels in Gastrointestinal Physiology and Pathology
    Guo, Jing
    Li, Li
    Chen, Feiyi
    Fu, Minhan
    Cheng, Cheng
    Wang, Meizi
    Hu, Jun
    Pei, Lixia
    Sun, Jianhua
    BIOMOLECULES, 2024, 14 (07)
  • [33] Mechanosensitive Piezo channels mediate the physiological and pathophysiological changes in the respiratory system
    Xiong, Huaiyu
    Yang, Jing
    Guo, Jun
    Ma, Aijia
    Wang, Bo
    Kang, Yan
    RESPIRATORY RESEARCH, 2022, 23 (01)
  • [34] Mechanosensitive Piezo channels mediate the physiological and pathophysiological changes in the respiratory system
    Huaiyu Xiong
    Jing Yang
    Jun Guo
    Aijia Ma
    Bo Wang
    Yan Kang
    Respiratory Research, 23
  • [35] The mechanosensitive Piezo1 channels contribute to the arterial medial calcification
    Szabo, Laszlo
    Balogh, Norbert
    Toth, Andrea
    Angyal, Agnes
    Gonczi, Monika
    Csiki, David Mate
    Toth, Csaba
    Balatoni, Ildiko
    Jeney, Viktoria
    Csernoch, Laszlo
    Dienes, Beatrix
    FRONTIERS IN PHYSIOLOGY, 2022, 13
  • [36] Touch, Tension, and Transduction - The Function and Regulation of Piezo Ion Channels
    Wu, Jason
    Lewis, Amanda H.
    Grandl, Jorg
    TRENDS IN BIOCHEMICAL SCIENCES, 2017, 42 (01) : 57 - 71
  • [37] Mechanosensitive unpaired innexin channels in C. elegans touch neurons
    Sangaletti, Rachele
    Dahl, Gerhard
    Bianchi, Laura
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2014, 307 (10): : C966 - C977
  • [38] Mechanosensitive ion channels in apoptosis and ferroptosis: focusing on the role of Piezo1
    Kim, Yong -Jae
    Hyun, Jeongeun
    BMB REPORTS, 2023, 56 (03) : 145 - 152
  • [39] Mechanosensitive meningeal nociception via Piezo channels: Implications for pulsatile pain in migraine?
    Mikhailov, Nikita
    Leskinen, Jarkko
    Fagerlund, Ilkka
    Poguzhelskaya, Ekaterina
    Giniatullina, Raisa
    Gafurov, Oleg
    Malm, Tarja
    Karjalainen, Tero
    Grohn, Olli
    Giniatullin, Rashid
    NEUROPHARMACOLOGY, 2019, 149 : 113 - 123
  • [40] Sequence Similarity Among Structural Repeats in the Piezo Family of Mechanosensitive Ion channels
    Hendargo, Kevin J. J.
    Patel, Ashay O. O.
    Chukwudozie, Onyeka S. S.
    Moreno-Hagelsieb, Gabriel
    Christen, J. Andres
    Medrano-Soto, Arturo
    Saier Jr., Milton H. H.
    MICROBIAL PHYSIOLOGY, 2023, 33 (01): : 49 - 62