Novel applications of quantitative MRI for the fetal brain

被引:17
作者
Clouchoux, Cedric [2 ]
Limperopoulos, Catherine [1 ,2 ,3 ,4 ]
机构
[1] Childrens Natl Med Ctr, Div Fetal & Transit Med, Washington, DC 20010 USA
[2] Childrens Natl Med Ctr, Div Diagnost Imaging & Radiol, Washington, DC 20010 USA
[3] McGill Univ, Montreal Neurol Inst, McConnell Brain Imaging Ctr, Montreal, PQ, Canada
[4] McGill Univ, Dept Neurol & Neurosurg, Montreal, PQ, Canada
关键词
Fetal brain; MRI; In vivo; Quantitative techniques; Brain injury; MAGNETIC-RESONANCE SPECTROSCOPY; APPARENT DIFFUSION-COEFFICIENT; IN-UTERO; CEREBRAL-CORTEX; HUMAN-FETUS; MAGNETOENCEPHALOGRAPHIC RECORDINGS; FUNCTIONAL-DEVELOPMENT; PREMATURE NEWBORNS; PRETERM INFANTS; GESTATION;
D O I
10.1007/s00247-011-2178-0
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The advent of ultrafast MRI acquisitions is offering vital insights into the critical maturational events that occur throughout pregnancy. Concurrent with the ongoing enhancement of ultrafast imaging has been the development of innovative image-processing techniques that are enabling us to capture and quantify the exuberant growth, and organizational and remodeling processes that occur during fetal brain development. This paper provides an overview of the role of advanced neuroimaging techniques to study in vivo brain maturation and explores the application of a range of new quantitative imaging biomarkers that can be used clinically to monitor high-risk pregnancies.
引用
收藏
页码:24 / 32
页数:9
相关论文
共 79 条
[1]   Prenatal MR diffusion-weighted imaging in a fetus with hemimegalencephaly [J].
Agid, R ;
Lieberman, S ;
Nadjari, M ;
Gomori, JM .
PEDIATRIC RADIOLOGY, 2006, 36 (02) :138-140
[2]   Diffusion tensor imaging with tract-based spatial statistics reveals local white matter abnormalities in preterm infants [J].
Anjari, Mustafa ;
Srinivasan, Latha ;
Allsop, Joanna M. ;
Hajnal, Joseph V. ;
Rutherford, Mary A. ;
Edwards, A. David ;
Counsell, Serena J. .
NEUROIMAGE, 2007, 35 (03) :1021-1027
[3]   Metabolic assessment of the brain using proton magnetic resonance spectroscopy in a growth-restricted human fetus: Case report [J].
Azpurua, Humberto ;
Alvarado, Arturo ;
Mayobre, Finita ;
Salom, Tamara ;
Copel, Joshua A. ;
Guevara-Zuloaga, Freddy .
AMERICAN JOURNAL OF PERINATOLOGY, 2008, 25 (05) :305-309
[4]   Demonstration of acute ischemic lesions in the fetal brain by diffusion magnetic resonance imaging [J].
Baldoli, C ;
Righini, A ;
Parazzini, C ;
Scotti, G ;
Triulzi, F .
ANNALS OF NEUROLOGY, 2002, 52 (02) :243-246
[5]   MR DIFFUSION TENSOR SPECTROSCOPY AND IMAGING [J].
BASSER, PJ ;
MATTIELLO, J ;
LEBIHAN, D .
BIOPHYSICAL JOURNAL, 1994, 66 (01) :259-267
[6]   Measures of folding applied to the development of the human fetal brain [J].
Batchelor, PG ;
Smith, ADC ;
Hill, DLG ;
Hawkes, DJ ;
Cox, TCS ;
Dean, AF .
IEEE TRANSACTIONS ON MEDICAL IMAGING, 2002, 21 (08) :953-965
[7]  
Berman J I, 2011, AJNR Am J Neuroradiol, V32, pE21, DOI 10.3174/ajnr.A1975
[8]   1ST MAGNETOENCEPHALOGRAPHIC RECORDINGS OF THE BRAIN ACTIVITY OF A HUMAN-FETUS [J].
BLUM, T ;
SALING, E ;
BAUER, R .
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1985, 92 (12) :1224-1229
[9]   Diffusion-weighted MR Imaging of the Placenta in Fetuses with Placental Insufficiency [J].
Bonel, Harald Marcel ;
Stolz, Bernhard ;
Diedrichsen, Lars ;
Frei, Kathrin ;
Saar, Bettina ;
Tutschek, Boris ;
Raio, Luigi ;
Surbek, Daniel ;
Srivastav, Sudesh ;
Nelle, Mathias ;
Slotboom, Johannes ;
Wiest, Roland .
RADIOLOGY, 2010, 257 (03) :810-819
[10]   Assessment of fetal distress based on magnetic resonance examinations:: Preliminary report [J].
Borowska-Matwiejczuk, K ;
Lemancewicz, A ;
Tarasów, E ;
Urban, J ;
Urban, R ;
Walecki, J ;
Kubas, B .
ACADEMIC RADIOLOGY, 2003, 10 (11) :1274-1282