A magnetic particle micro-trap for large trapping surfaces

被引：5

作者：

Gooneratne, Chinthaka P. ^{[1
]}

Liang, Cai ^{[1
]}

Giouroudi, Ioanna ^{[2
]}

Kosel, Juergen ^{[1
]}

机构：

[1] King Abdullah Univ Sci & Technol, Div Phys Sci & Engn, Thuwal 23955, Saudi Arabia

[2] Vienna Univ Technol, Inst Sensor & Actuator Syst, A-1040 Vienna, Austria

来源：

EUROSENSORS XXV | 2011年 / 25卷

关键词：

magnetic particle; micro-trap; magnetic force; cytometry;

D O I：

10.1016/j.proeng.2011.12.296

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

Manipulation of micron-size magnetic particles of the superparamagnetic type contributes significantly in many applications like controlling the antibody/antigen binding process in immunoassays. Specifically, more target biomolecules can be attached/tagged and analyzed since the three dimensional structure of the magnetic particles increases the surface to volume ratio. Additionally, such biomolecular-tagged magnetic particles can be easily manipulated by an external magnetic field due to their superparamagnetic behavior. Therefore, magnetic particle-based immunoassays are extensively applied in micro-flow cytometry. The design of a square-loop micro-trap as a magnetic particle manipulator as well as numerical and experimental analysis is presented. Experimental results showed that the micro-trap could successfully trap and concentrate magnetic particles from a large to a small area with a high spatial range. (C) 2011 Published by Elsevier Ltd.

引用

页数：4

共 4 条

[1] Cell manipulation with magnetic particles toward microfluidic cytometry [J].

Liu, Chengxun ;

Stakenborg, Tim ;

Peeters, Sara ;

Lagae, Liesbet .

JOURNAL OF APPLIED PHYSICS, 2009, 105 (10)

[2] Manipulation of ferrofluid droplets using planar coils [J].

Nguyen, Nam-Trung ;

Ng, Kon Meng ;

Huang, Xiaoyang .

APPLIED PHYSICS LETTERS, 2006, 89 (05)

[3] Magnetism and microfluidics [J].

Pamme, N .

LAB ON A CHIP, 2006, 6 (01) :24-38

[4] An on-chip magnetic bead separator for biocell sorting [J].

Rong, Rong ;

Choi, Jin-Woo ;

Ahn, Chong H. .

JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 2006, 16 (12) :2783-2790

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