Reconstructing time-to-event data from published Kaplan-Meier curves

被引:174
作者
Wei, Yinghui [1 ]
Royston, Patrick [2 ]
机构
[1] Plymouth Univ, Sch Comp Elect & Math, Ctr Math Sci, Plymouth, Devon, England
[2] UCL, MRC Clin Trials Unit, London, England
基金
英国医学研究理事会;
关键词
st0498; ipdfc; time-to-event data; Kaplan-Meier curves; hazard ratios; MEAN SURVIVAL-TIME; METAANALYSIS; TRIALS;
D O I
10.1177/1536867X1701700402
中图分类号
O1 [数学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 0701 ; 070101 ;
摘要
Hazard ratios can be approximated by data extracted from published Kaplan-Meier curves. Recently, this curve approach has been extended beyond hazard-ratio approximation with the capability of constructing time-to-event data at the individual level. In this article, we introduce a command, ipdfc, to implement the reconstruction method to convert Kaplan-Meier curves to time-to-event data. We give examples to illustrate how to use the command
引用
收藏
页码:786 / 801
页数:16
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