Management of Differentiated Thyroid Cancer: The Standard of Care

被引：23

作者：

Avram, Anca M. ^{[1
,2
]}

Zukotynski, Katherine ^{[3
,4
,5
,6
]}

Nadel, Helen Ruth ^{[7
]}

Giovanella, Luca ^{[8
,9
,10
,11
]}

机构：

[1] Univ Michigan, Dept Radiol, Div Nucl Med, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Div Endocrinol, Dept Internal Med, Ann Arbor, MI 48109 USA

[3] McMaster Univ, Dept Med, Hamilton, ON, Canada

[4] McMaster Univ, Dept Radiol, Hamilton, ON, Canada

[5] Western Univ, Schulich Sch Med & Dent, Dept Med Imaging, London, ON, Canada

[6] Univ British Columbia, Dept Radiol, Vancouver, BC, Canada

[7] Stanford Univ, Sch Med, Lucile Packard Childrens Hosp Stanford, Stanford, CA 94305 USA

[8] Imaging Inst Southern Switzerland, Clin Nucl Med, Bellinzona, Switzerland

[9] Imaging Inst Southern Switzerland, Competence Ctr Thyroid Dis, Bellinzona, Switzerland

[10] Univ Hosp, Clin Nucl Med, Zurich, Switzerland

[11] Univ Zurich, Zurich, Switzerland

来源：

JOURNAL OF NUCLEAR MEDICINE | 2022年 / 63卷 / 02期

关键词：

differentiated thyroid cancer; state of the art; guidelines; clinical management; PREABLATION 131-I SCANS; RADIOIODINE THERAPY; HORMONE WITHDRAWAL; AMERICAN-COLLEGE; NECK DISSECTION; I-131; THERAPY; PAPILLARY; CARCINOMA; ASSOCIATION; METASTASES;

D O I：

10.2967/jnumed.121.262402

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

In the past decade, the management of differentiated thyroid cancer (DTC) underwent a paradigm shift toward the use of risk stratification with the goal of maximizing the benefit and minimizing the morbidity of radioiodine (I-131) therapy. I-131 therapy is guided by information derived from surgical histopathology, molecular markers, postoperative diagnostic radioiodine scintigraphy, and thyroglobulin levels. I-131 is used for diagnostic imaging and therapy of DTC based on physiologic sodium-iodine symporter expression in normal and neoplastic thyroid tissue. We summarize the essential information at the core of multidisciplinary DTC management, which emphasizes individualization of I-131 therapy according to the patient's risk for tumor recurrence.

引用

页码：189 / 195

页数：7

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[1] PAPILLARY THYROID-CARCINOMA ETIOLOGY, ASSESSMENT, AND THERAPY [J].