Stereoselective γ-lactam synthesis via palladium-catalysed intramolecular allylation

被引：27

作者：

Craig, D

Hyland, CJT

Ward, SE

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Dept Med, London SW7 2AZ, England

[2] GlaxoSmithKline Res & Dev Ltd, Harlow CM19 5AW, Essex, England

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 27期

关键词：

D O I：

10.1039/b504731e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel route to the synthesis of 3-(tolylsulfonyl)-4,5-cis-disubstituted gamma-lactams using a diastereoselective palladium-catalysed intramolecular allylation of amino acid-derived allylic carbonates has been developed.

引用

页码：3439 / 3441

页数：3

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