Antibody-functionalized SERS tags with improved sensitivity

被引：32

作者：

Guarrotxena, Nekane ^{[1
,2
]}

Bazan, Guillermo C. ^{[2
]}

机构：

[1] CSIC, Inst Ciencia & Tecnol Polimeros, E-28006 Madrid, Spain

[2] Univ Calif Santa Barbara, Dept Chem & Biochem & Mat, Inst Polymers & Organ Solids, Santa Barbara, CA 93106 USA

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 31期

基金：

美国国家科学基金会;

关键词：

ENHANCED RAMAN-SPECTROSCOPY; GOLD NANOPARTICLES; ULTRASENSITIVE DETECTION; PROTEIN RECOGNITION; SINGLE-MOLECULE; DNA; NANOSCALE;

D O I：

10.1039/c1cc12659h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Protein detection at the femtomolar level can be achieved by using metallic nanoparticle assemblies that function as surface enhanced Raman spectroscopy reporters and that contain suitable surface-bound recognition elements. Proper control of the interaction between nanoparticles within the assemblies is critical for achieving this performance.

引用

页码：8784 / 8786

页数：3

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