Unusual access to 5-methoxy or 5,5-dimethoxy-4-methyl-3-pyrrolin-2-ones from chlorinated 4-methyl-pyrrolidin-2-ones

被引：7

作者：

Bellesia, F

De Buyck, L

Colucci, MV

Ghelfi, F

Laureyn, I

Libertini, E

Mucci, A

Pagnoni, UM

Pinetti, A

Rogge, TM

Stevens, CV

机构：

[1] Univ Modena, Dipartimento Chim, I-41100 Modena, Italy

[2] Univ Ghent, Dept Organ Chem, Fac Agr & Appl Biol Sci, B-9000 Ghent, Belgium

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 27期

关键词：

pyrrolidinones; pyrrolinones; lactams; eliminations;

D O I：

10.1016/S0040-4039(01)00792-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of N-substituted 4-methyl-2-pyrrolidinones, carrying not less than two chlorine atoms on the C(3) and C(6) carbons afforded with alkaline methoxide in methanol, under mild conditions, the corresponding 5-methoxy or 5,5-dimethoxy-4-methyl-3-pyrrolin-2-ones in satisfactory yields. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

收藏

页码：4573 / 4575

页数：3

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