Gadobenate Dimeglumine-Enhanced Liver Magnetic Resonance Imaging: Value of Hepatobiliary Phase for the Detection of Focal Liver Lesions

被引：13

作者：

Fu, Guo-li ^{[1
]}

Du, Yong ^{[1
]}

Zee, Chi-shing ^{[2
]}

Yang, Han-feng ^{[1
]}

Li, Yang ^{[1
]}

Duan, Ru-gang ^{[1
]}

Zeng, Nan-lin ^{[1
]}

Xiao, Dong-Mei ^{[1
]}

机构：

[1] N Sichuan Med Coll, Affiliated Hosp, Dept Radiol, Nanchong 637000, Sichuan, Peoples R China

[2] Univ So Calif, Keck Sch Med, Dept Radiol, Los Angeles, CA 90033 USA

来源：

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY | 2012年 / 36卷 / 01期

关键词：

gadobenate dimeglumine; focal liver lesions; magnetic resonance imaging; hepatobiliary phase; GD-BOPTA; HEPATIC-LESIONS; EFFICACY; MRI; CT;

D O I：

10.1097/RCT.0b013e31823dc139

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Objective: The objective of the study was to determine the value of addition of hepatobiliary phase to dynamic gadobenate dimeglumine (Gd-BOPTA)-enhanced imaging for the detection of focal liver lesions (nodules with diameter <= 3.0 cm). Methods: Routine nonenhanced magnetic resonance images were obtained in 25 patients with focal liver lesions suggested by ultrasonography and/or computed tomography. T1-weighted dynamic gradient-echo images were acquired immediately and 100 minutes after bolus injection of Gd-BOPTA. The number of the lesions detected by T1-weighted imaging, T2-weighted imaging, diffusion-weighted imaging, dynamic contrast-enhanced, and delayed hepatobiliary-phase imaging was counted, respectively. Contrast-to-noise ratios were measured for all the sequences including delayed hepatobiliary-phase imaging. The signal intensity and morphologic features of liver parenchyma and lesions were recorded and analyzed. Results: There were 7 patients with hepatocellular carcinomas, 6 with hemangiomas, 7 with metastases, and 5 with cholangiocarcinomas. The delayed hepatobiliary-phase imaging showed a homogeneous enhancement of liver parenchyma and distinctive enhancement features of focal liver lesions. The delayed hepatobiliary-phase imaging was better than diffusion-weighted imaging for the detection of focal liver lesions (P < 0.05). Conclusion: The addition of hepatobiliary-phase imaging to Gd-BOPTA-enhanced dynamic imaging increased the sensitivity and accuracy for the detection of focal hepatic lesions.

引用

页码：14 / 19

页数：6

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