The RAISE Connection Program for Early Psychosis Secondary Outcomes and Mediators and Moderators of Improvement

被引：29

作者：

Marino, Leslie ^{[1
]}

Nossel, Ilana ^{[1
]}

Choi, Jean C. ^{[1
]}

Nuechterlein, Keith ^{[2
,3
]}

Wang, Yuanjia ^{[1
]}

Essock, Susan ^{[1
]}

Bennett, Melanie ^{[4
]}

McNamara, Karen ^{[4
]}

Mendon, Sapna ^{[1
]}

Dixon, Lisa ^{[1
]}

机构：

[1] Columbia Univ, New York State Psychiat Inst, Dept Psychiat, New York, NY 10027 USA

[2] Univ Calif Los Angeles, Dept Psychiat & Biobehav Sci, Los Angeles, CA 90024 USA

[3] Univ Calif Los Angeles, Dept Psychol, Los Angeles, CA 90024 USA

[4] Univ Maryland, Sch Med, Dept Psychiat, Baltimore, MD 21201 USA

来源：

JOURNAL OF NERVOUS AND MENTAL DISEASE | 2015年 / 203卷 / 05期

基金：

美国国家卫生研究院;

关键词：

First-episode psychosis; early intervention; recovery; 1ST EPISODE SCHIZOPHRENIA; 1ST-EPISODE PSYCHOSIS; SERVICE DISENGAGEMENT; PREDICTORS; LIFE; RECOVERY; VALIDITY; SCALE; RELIABILITY; CARE;

D O I：

10.1097/NMD.0000000000000293

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The aims of this study were to explore secondary outcomes of a coordinated specialty care program for persons with early psychosis, including quality of life and recovery, as well as to explore mediators and moderators of improvement in occupational and social functioning and symptoms. Sixty-five individuals across two sites were enrolled and received services for up to 2 years. Trajectories for individuals' outcomes over time were examined using linear and quadratic mixed-effects models with repeated measures. In addition, baseline prognostic factors of participant improvement in social and occupational functioning were explored based on previous literature and expert opinion of the analytic team. Results demonstrate that the program was effective in improving quality of life and recovery over time. Furthermore, processing speed was identified as a significant moderator of improvement in occupational Global Assessment of Function, and treatment fidelity, engagement, and family involvement were identified as mediators of improvement in social and occupational functioning.

引用

页码：365 / 371

页数：7

共 49 条

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