Chitin and chitosan preparation from shrimp shells Penaeus monodon and its human ovarian cancer cell line, PA-1

被引:128
|
作者
Srinivasan, Haripriya [1 ]
Velayutham, Kanayairam [1 ]
Ravichandran, Ramanibai [1 ]
机构
[1] Univ Madras, Dept Zool, Unit Aquat Biodivers, Guindy Campus, Madras 600025, Tamil Nadu, India
关键词
Chitin; Chitosan; Penaeus monodon; FTIR; ALPHA-CHITIN; ANTIOXIDANT; EXTRACTION; RECOVERY; WASTE;
D O I
10.1016/j.ijbiomac.2017.09.035
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In the present study, chitin and chitosan preparation from shrimp shells Penaeus mondon and its ovarian cancer cell line (PA-1). FTIR spectrum sharp absorption peak at 1655 cm(-1) is assigned to ketone C=O (alpha) unsaturated with chitosan. X-ray diffraction showed the presence of chitin and chitosan were strongest peak at 18.91 degrees (beta) and 29.75 degrees (alpha) characters. SEM observations of chitin and chitosan surface morphologies of P. monodon showed that microfibril and porous structures. Anticancer activity of chitin and chitosan against human ovarian cancer cell line showed that chitosan an exhibited notable higher activity than chitin. Anticancer activity of aquacultural waste of shrimp shells mediated chitosan, which was proved to be good novel pharmaceutical industries. (C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码:662 / 667
页数:6
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