Establishment and characterization of a new canine mast cell tumor cell line

被引:27
作者
Ishiguro, T [1 ]
Kadosawa, T
Mori, K
Takagi, S
Okumura, M
Fujinaga, T
机构
[1] Hokkaido Univ, Grad Sch Vet Med, Dept Vet Clin Sci, Lab Vet Surg, Sapporo, Hokkaido 0600818, Japan
[2] Hokkaido Univ, Grad Sch Vet Med, Dept Biomed Sci, Lab Anat, Sapporo, Hokkaido 0600818, Japan
关键词
canine; cell line; mast cell tumor;
D O I
10.1292/jvms.63.1031
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
A new cell line (CoMS) was established from a 3-year-old male mongrel dog with mast cell tumor of the oral mucosa. coma. cells grow in suspension with a doubling time of 27.0 +/- 0.7 hr, The cytoplasmic granules were formalin-sensitive, showed diverse appearances in their ultrastructural findings and contained heparin proteoglycan and neutral protease chymase. Calcium ionophore A23187, substance P and concanavalin A caused significant histamine release from CoMS cells, while compound 48/80 failed to release histamine. This cell line will make an available source for studies on canine mast cell tumors.
引用
收藏
页码:1031 / 1034
页数:4
相关论文
共 50 条
[21]   Establishment and characterization of a mantle cell lymphoma cell line [J].
Jeon, HJ ;
Kim, CW ;
Yoshino, T ;
Akagi, T .
BRITISH JOURNAL OF HAEMATOLOGY, 1998, 102 (05) :1323-1326
[22]   Establishment and characterization of a canine sebaceous epithelial cell line derived from an eyelid mass [J].
Matsuda, Akira ;
Mitsui, Ikki ;
Shimizu, Yuki ;
Kanda, Teppei ;
Ohnishi, Akihiro ;
Miyabe, Masahiro ;
Itoh, Yoshiki .
JOURNAL OF VETERINARY MEDICAL SCIENCE, 2020, 82 (11) :1577-1584
[23]   Establishment of a new cell line of canine inflammatory mammary cancer: IMC-118 [J].
Gao, Hongbo ;
Zhou, Han ;
Gao, Yiming ;
He, Lixin ;
Li, Wenxuan ;
Xu, Meixia ;
Feng, Huili ;
Feng, Xiujuan ;
Qiu, Changwei .
VETERINARY AND COMPARATIVE ONCOLOGY, 2022, 20 (03) :679-687
[24]   Establishment and characterization of four canine melanoma cell lines [J].
Inoue, K ;
Ohashi, E ;
Kadosawa, T ;
Hong, SH ;
Matsunaga, S ;
Mochizuki, M ;
Nishimura, R ;
Sasaki, N .
JOURNAL OF VETERINARY MEDICAL SCIENCE, 2004, 66 (11) :1437-1440
[25]   Establishment and characterization of a new human glioblastoma cell line, NYGM. [J].
Nuki Y. ;
Uchinokura S. ;
Miyata S. ;
Fukushima T. ;
Hamasuna R. ;
Nakano S. ;
Wakisaka S. ;
Akiyama Y. ;
Itoh H. ;
Kataoka H. .
Human Cell, 2004, 17 (3) :145-150
[26]   Establishment and characterization of a porcine B cell lymphoma cell line [J].
Rahe, Michael C. ;
Dvorak, Cheryl M. T. ;
Wiseman, Barry ;
Martin, Daniel ;
Murtaugh, Michael P. .
EXPERIMENTAL CELL RESEARCH, 2020, 390 (02)
[27]   Establishment and characterization of a spindle cell squamous carcinoma cell line [J].
Kudo, Yasusei ;
Ogawa, Ikuko ;
Kitagawa, Masae ;
Kitajima, Shojiro ;
Siriwardena, B. S. M. Samadarani ;
Aobara, Noriko ;
Matsuda, Chika ;
Miyauchi, Mutsumi ;
Takata, Takashi .
JOURNAL OF ORAL PATHOLOGY & MEDICINE, 2006, 35 (08) :479-483
[28]   Genetic alterations of KIT during clonal expansion and subsequent acquisition of resistance to toceranib in a canine mast cell tumor cell line [J].
Kurita, Sena ;
Miyamoto, Ryo ;
Tani, Hiroyuki ;
Kobayashi, Masato ;
Sasaki, Takashi ;
Tamura, Kyoichi ;
Bonkobara, Makoto .
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 2019, 42 (06) :673-681
[29]   Establishment and characterization of a cell line from a feline histiocytic sarcoma [J].
Miyamoto, Ryo ;
Kurita, Sena ;
Tani, Hiroyuki ;
Kobayashi, Masato ;
Sugiura, Soudai ;
Shigihara, Kae ;
Sato, Yuka ;
Tanaka, Yoshikazu ;
Tamura, Kyoichi ;
Bonkobara, Makoto .
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 2018, 201 :72-76
[30]   Establishment and characterization of a human cholangiocarcinoma cell line [J].
Ma, Stephanie ;
Hu, Liang ;
Huang, Xiao-Hui ;
Cao, Liang-Qi ;
Chan, Kwok Wah ;
Wang, Qian ;
Guan, Xin-Yuan .
ONCOLOGY REPORTS, 2007, 18 (05) :1195-1200