Mathematical modelling of Toxoplasma gondii transmission: A systematic review

被引：18

作者：

Deng, Huifang ^{[1
]}

Cummins, Rachel ^{[1
]}

Schares, Gereon ^{[2
]}

Trevisan, Chiara ^{[3
]}

Enemark, Heidi ^{[4
]}

Waap, Helga ^{[5
]}

Srbljanovic, Jelena ^{[6
]}

Djurkovic-Djakovic, Olgica ^{[6
]}

Pires, Sara Monteiro ^{[7
]}

van der Giessen, Joke W. B. ^{[1
]}

Opsteegh, Marieke ^{[1
]}

机构：

[1] Natl Inst Publ Hlth & Environm, Ctr Infect Dis Control Zoonoses & Environm Microb, NL-3720 BA Bilthoven, Netherlands

[2] Fed Res Inst Anim Hlth, Friedrich Loeffler Inst, Inst Epidemiol, D-17493 Greifswald, Insel Riems, Germany

[3] Inst Trop Med, Dept Biomed Sci, Nationalestr 155, B-2000 Antwerp, Belgium

[4] Norwegian Vet Inst, Dept Anim Hlth & Food Safety, POB 750, NO-0106 Oslo, Norway

[5] Inst Nacl Invest Agr & Vet, Lab Parasitol, Av Republ, P-2780157 Oeiras, Portugal

[6] Univ Belgrade, Ctr Excellence Food & Vector Borne Zoonoses, Inst Med Res, Natl Reference Lab Toxoplasmosis, Dr Subotica 4, Belgrade 11129, Serbia

[7] Tech Univ Denmark, Natl Food Inst, Kemitorvet 201, DK-28001 Lyngby, Denmark

来源：

FOOD AND WATERBORNE PARASITOLOGY | 2021年 / 22卷

关键词：

Zoonoses; Mathematical model; Toxoplasmosis; Transmission; Modelling; COUPLING WITHIN-HOST; RURAL AREA; DYNAMICS; OOCYSTS; INFECTION; OUTBREAK; DISEASE; CATS; BIFURCATIONS; STRATEGIES;

D O I：

10.1016/j.fawpar.2020.e00102

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Background: Toxoplasma gondii is a ubiquitous protozoan parasite that can infect virtually all warm-blooded animals. It is the causative agent of toxoplasmosis, a significant public health issue worldwide. Mathematical models are useful to study the transmission dynamics of T. gondii infection in different settings, and may be used to compare the effectiveness of prevention measures. Methods: To obtain an overview of existing mathematical models for transmission of T. gondii, a systematic review was undertaken. The review was conducted according to an a priori protocol and the results were reported according to the PRISMA guidelines. Specific search terms were developed and used in the search of three databases (Scopus, PubMed, and Embase). Results: In total, 484 unique records were retrieved from the systematic search. Among them, 15 studies that used mathematical models to study the transmission of T. gondii. These studies were categorized into four groups based on the primary aims: dynamics of transmission (n = 8), intervention (n = 5), spatial distribution (n = 1), and outbreak investigation (n = 1). Conclusions: Considering the high disease burden caused by T. gondii, the number of studies using mathematical models to understand the transmission dynamics of this parasite and to evaluate the effectiveness of intervention measures was only 15. This systematic review provides an overview of existing mathematical models and identifies the data gaps for model building. The results from this study can be helpful for further development of mathematical models and improved understanding of the transmission dynamics of T. gondii infection. (C) 2020 Published by Elsevier Inc. on behalf of International Association of Food and Waterborne Parasitology.

引用

页数：11

共 61 条

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