Lipidated polymers for the stabilization of cubosomes: nanostructured drug delivery vehicles

被引:14
|
作者
Grace, James L. [1 ,2 ]
Alcaraz, Nicolas [1 ,2 ]
Truong, Nghia P. [1 ,2 ]
Davis, Thomas P. [1 ,2 ,3 ]
Boyd, Ben J. [1 ,2 ]
Quinn, John F. [1 ,2 ]
Whittaker, Michael R. [1 ,2 ]
机构
[1] Monash Univ, Monash Inst Pharmaceut Sci, ARC Ctr Excellence Convergent Bionano Sci & Techn, Parkville, Vic 3052, Australia
[2] Monash Univ, Monash Inst Pharmaceut Sci, Drug Delivery Disposit & Dynam Theme, Parkville, Vic 3052, Australia
[3] Univ Warwick, Dept Chem, Coventry ULCV4 7AL, W Midlands, England
基金
澳大利亚研究理事会;
关键词
LIVING RADICAL POLYMERIZATION; LIQUID-CRYSTALLINE NANOPARTICLES; SET-LRP; STERIC STABILIZERS; COPOLYMERS; ETHER; 25-DEGREES-C; METHACRYLATE; DISPERSIONS; PHYTANTRIOL;
D O I
10.1039/c7cc05842j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Lipidated polymers, like their protein counterparts, may be useful in fields as diverse as biochemistry and drug delivery. As such, strategies for preparing lipidated polymers with defined molecular architecture are clearly warranted. Herein, we describe a broadly-applicable methodology for synthesizing such lipidated materials, and demonstrate how they can be applied to the preparation of nanostructured drug delivery vehicles.
引用
收藏
页码:10552 / 10555
页数:4
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