Palladium-catalyzed site-selective arylation of symmetric dichlorobenzaldehyde to non-symmetric diaryl benzaldehyde via Suzuki coupling

被引：1

作者：

Dey, Raju ^{[1
]}

Ranu, Brindaban C. ^{[1
]}

机构：

[1] Indian Assoc Cultivat Sci, Dept Organ Chem, Kolkata 700032, India

来源：

TETRAHEDRON LETTERS | 2012年 / 53卷 / 13期

关键词：

Site-selectivity; Suzuki coupling; Pd(II)-catalysis; Arylation; Nonsymmetric 2,6-diaryl-benzaldehyde; MIYAURA REACTIONS; HALOGENATED NITROGEN; ARYL; TERPHENYLS; GROWTH; OXYGEN;

D O I：

10.1016/j.tetlet.2012.01.014

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Arylation of 2,6-dichlorobenzaldehyde by aryl boronic acids via site-selective Suzuki coupling catalyzed by PdCl2 supported on 4 A molecular sieves produces 2-aryl-6-chlorobenzaldehyde which on subsequent coupling with a different aryl boronic acid in the presence of Pd(OAc)(2)-NHC ligand leads to non-symmetric diaryl benzaldehyde in good overall yield. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：1558 / 1560

页数：3

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