Synthesis, characterization, thermal stability and antimicrobial activities of transition metal complexes of 8-[2-amino-2-(4-hydroxyphenyl)-acetyl]amino-4-methyl-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid

The complexes of 8-[2-amino-2-(4-hydroxyphenyl)-acetyl]amino-4-methyl-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid (L) With Fe-III, Ni-II and Ru-III of composition [MLX2] (M = Fe-III, Ni-II and Ru-III; X = Cl) were prepared and characterized by elemental analysis, molar conductance, magnetic susceptibility, IR, UV-Visible, Mass, SEM and thermogravimetric studies. As elemental analysis suggests ML stoichiometry for all metals, conductivity data suggests that all the complexes are non-electrolyte in nature. Similarly, magnetic susceptibility, spectral and thermal studies suggest that all the complexes possess octahedral geometry. The synthesized metal complexes were screened for their antimicrobial activities against bacteria Escherichia coli and Staphylococcus aureus. The results were found to exhibit potent biological activity against both bacteria which Increased in the forms of their metal complexes.