Racial disparities after vascular trauma are age-dependent

被引:12
|
作者
Hicks, Caitlin W. [1 ]
Canner, Joseph K. [1 ]
Zarkowsky, Devin S. [1 ,2 ]
Arhuidese, Isibor [1 ]
Obeid, Tammam [1 ]
Malas, Mahmoud B. [1 ]
机构
[1] Johns Hopkins Med Inst, Div Vasc & Endovasc Therapy, Baltimore, MD 21205 USA
[2] Dartmouth Hitchcock Med Ctr, Dept Surg, Lebanon, NH 03766 USA
关键词
INJURY SEVERITY SCORE; LOWER-EXTREMITY ISCHEMIA; ICD-9 DIAGNOSIS CODES; NATIONAL TRAUMA; DATA-BANK; PEDIATRIC TRAUMA; INSURANCE STATUS; FUNCTIONAL OUTCOMES; BRAIN-INJURY; RISK-FACTORS;
D O I
10.1016/j.jvs.2016.01.049
中图分类号
R61 [外科手术学];
学科分类号
摘要
Objective: Different racial disparities exist between white and black all-cause trauma patients depending on their age group; however, the effects of race and age on outcomes after vascular trauma are unknown. We assessed whether the previously described age-dependent racial disparities after all-cause trauma persist in the vascular trauma population. Methods: Vascular trauma patients were identified from the Nationwide Inpatient Sample (January 2005 to December 2012) using International Classification of Diseases-Ninth Edition codes. Univariable and multivariable analyses were used to compare in-hospital mortality and amputation for blacks vs whites for younger (16-64 years) and older ( years) age groups. Results: Black patients (n = 937) were younger, more frequently male, without insurance, and suffered from more penetrating and nonaccidental injuries than white patients (n = 1486; P < .001). On univariable analysis, blacks had a significantly higher risk of death (odds ratio, [OR], 1.78; 95% confidence interval [CI], 1.16-2.74) and a significantly lower risk of amputation (OR, 0.54; 95% CI, 0.38-0.77), but these differences were not sustained after adjusting for baseline differences between groups. When stratified by age, there were significant racial disparities in mortality and amputation on univariable analysis. After risk adjustment, these differences persisted in the older group (mortality: OR, 5.95; 95% CI, 1.42-25.0; amputation: OR, 4.21; 95% CI, 1.28-13.6; P < .001) but not the younger group (mortality: OR, 1.31; 95% CI, 0.71-2.42; amputation: OR, 0.92; 95% CI, 0.58-1.46; P = not significant). Differences in survival and amputation after vascular trauma appear to be related to a higher prevalence of nonaccidental penetrating injuries in the younger black population. Race was the single greatest predictor of poor outcomes in the older population (P <= .008). Conclusions: Older black patients are nearly five-times more likely to experience death or amputation after vascular trauma than their white counterparts. Contrary to reports suggesting that younger white patients have better outcomes after all-cause trauma than younger black patients, racial disparities among patients with traumatic vascular injuries appear to be confined to the older age group after risk adjustment.
引用
收藏
页码:418 / 424
页数:7
相关论文
共 50 条
  • [31] Age-dependent disparities of myocardial infarction aetiology and mortality: how are the young and the elderly affected?
    Lux, A.
    Bacsardi, F.
    Edes, I. F.
    Becker, D.
    Merkely, B.
    Ruzsa, Z.
    EUROPEAN HEART JOURNAL, 2018, 39 : 892 - 892
  • [32] Age-dependent telomere attrition as a potential indicator of racial differences in renal growth patterns
    Tchakmakjian, L
    Gardner, JP
    Wilson, PD
    Kimura, M
    Skurnick, J
    Zielke, HR
    Aviv, A
    NEPHRON EXPERIMENTAL NEPHROLOGY, 2004, 98 (03): : E82 - E88
  • [33] AGE-DEPENDENT LIDOCAINE DISPOSITION AFTER MYOCARDIAL-INFARCTION
    CUSSON, J
    NATTEL, S
    LAWAND, S
    TALAJIC, M
    CLINICAL RESEARCH, 1984, 32 (02): : A240 - A240
  • [34] Is HLA Sensitization after Pediatric Thoracic Transplantation Age-Dependent?
    Urschell, S.
    Meyer, S. R.
    Larson, I.
    Derkatz, K.
    Tinckam, K.
    Nuebel, J.
    Birnbaum, J.
    Campbell, P. M.
    West, L. J.
    JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2009, 28 (02): : S233 - S233
  • [35] Age-dependent chronic rejection after experimental heart transplantation
    Holinski, Sebastian
    Modersohn, Diethelm
    Proch, Corinna
    Meyer, Rudolf
    Konertz, Wolfgang
    JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2006, 25 (09): : 1099 - 1102
  • [36] AN ORDERING POLICY WITH AGE-DEPENDENT MINIMAL REPAIR AND AGE-DEPENDENT RANDOM REPAIR COSTS
    SHEU, SH
    LIOU, CT
    MICROELECTRONICS AND RELIABILITY, 1992, 32 (08): : 1105 - 1113
  • [37] VASCULAR COMPRESSION IN THE THORACIC OUTLET - AGE-DEPENDENT NORMATIVE VALUES IN NONINVASIVE TESTING
    COLON, E
    WESTDORP, R
    JOURNAL OF CARDIOVASCULAR SURGERY, 1988, 29 (02): : 166 - 171
  • [38] Glutathione Peroxidase-1-Deficiency Enhances Age-Dependent Vascular Dysfunction
    Oelze, Matthias
    Kroeller-Schoen, Swenja
    Bachschmid, Markus
    Lubos, Edith
    Doppler, Christopher
    Daub, Steffen
    Schuff, Alexandra
    Scholz, Alexander
    Torzewski, Michael
    Wenzel, Philip
    Lackner, Karl J.
    Muenzel, Thomas
    Daiber, Andreas
    FREE RADICAL BIOLOGY AND MEDICINE, 2011, 51 : S77 - S77
  • [39] Correction: Corrigendum: Age-dependent modulation of vascular niches for haematopoietic stem cells
    Anjali P. Kusumbe
    Saravana K. Ramasamy
    Tomer Itkin
    Maarja Andaloussi Mäe
    Urs H. Langen
    Christer Betsholtz
    Tsvee Lapidot
    Ralf H. Adams
    Nature, 2016, 539 : 314 - 314
  • [40] Virtual blunt injury of human thorax: age-dependent response of vascular system
    Beklemysheva, Katerina A.
    Danilov, Alexander A.
    Petrov, Igor B.
    Salamatova, Victoria Yu.
    Vassilevski, Yuri V.
    Vasyukov, Alexey V.
    RUSSIAN JOURNAL OF NUMERICAL ANALYSIS AND MATHEMATICAL MODELLING, 2015, 30 (05) : 259 - 268