1,3-dipolar cycloaddition on solid supports:: nitrone approach towards isoxazolidines and isoxazolines and subsequent transformations

被引：170
作者：
Rück-Braun, K [1 ]
Freysoldt, THE [1 ]
Wierschem, F [1 ]
机构：
[1] Tech Univ Berlin, Inst Chem, D-10623 Berlin, Germany
来源：
CHEMICAL SOCIETY REVIEWS | 2005年 / 34卷 / 06期
关键词：
D O I：
10.1039/b311200b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
1,3-Dipolar cycloaddition reactions of nitrones with alkenes and alkynes are well-studied reactions in solution-phase organic chemistry. However, the number of studies concerned with their application in solid-phase organic synthesis is rather low compared to other 1,3-dipoles, e.g. azides or nitrile oxides. This tutorial review aims to summarise the main approaches towards the application of nitrones in 1,3-dipolar cycloaddition reactions on solid supports in addition to subsequent transformations with polymer-bound isoxazolidines and reactions using polymer-bound catalysts.
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页码：507 / 516
页数：10
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