Vitamin K and vascular calcifications

被引：9

作者：

Fodor, D. ^{[1
]}

Albu, A. ^{[1
]}

Poanta, L. ^{[1
]}

Porojan, M. ^{[1
]}

机构：

[1] Univ Med & Pharm, Clin Iuliu Hatieganu, Cluj Napoca, Romania

来源：

ACTA PHYSIOLOGICA HUNGARICA | 2010年 / 97卷 / 03期

关键词：

vitamin K-1; vitamin K-2; matrix Gla protein; vascular calcification; vitamin K-dependent proteins; MATRIX GLA-PROTEIN; CORONARY-HEART-DISEASE; ARTERIAL VESSEL WALL; MORPHOGENETIC PROTEIN-2; CARDIOVASCULAR-DISEASE; COAGULATION VITAMIN; MENAQUINONE-4; PHYLLOQUINONE; MECHANISMS; TISSUE;

D O I：

10.1556/APhysiol.97.2010.3.2

中图分类号：

学科分类号：

摘要：

The role of vitamin K in the synthesis of some coagulation factors is well known. The implication of vitamin K in vascular health was demonstrated in many surveys and studies conducted over the past years on the vitamin K-dependent proteins non-involved in coagulation processes. The vitamin K-dependent matrix Gla protein is a potent inhibitor of the arterial calcification, and may become a non-invasive biochemical marker for vascular calcification. Vitamin K-2 is considered to be more important for vascular system, if compared to vitamin K-1. This paper is reviewing the data from recent literature on the involvement of vitamin K and vitamin K-dependent proteins in cardiovascular health.

引用

页码：256 / 266

页数：11

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