RETRACTED: Polymer nanodiscs and macro-nanodiscs of a varying lipid composition (Retracted article. See vol. 54, pg. 14033, 2018)

被引:38
|
作者
Ramadugu, Venkata Sudheer Kumar
Di Mauro, Giacomo Maria
Ravula, Thirupathi
Ramamoorthy, Ayyalusamy [1 ]
机构
[1] Univ Michigan, Biophys Program, Ann Arbor, MI 48109 USA
关键词
DETERGENT-FREE ISOLATION; MEMBRANE-PROTEINS; NMR; SOLUBILIZATION; RECONSTITUTION; NANOPARTICLES; MODEL; SIZE;
D O I
10.1039/c7cc06409h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Polymer lipid nanodiscs have enabled some exciting structural biology and nanobiotechnology applications. The use of a small molecular weight polymer (SMA-EA) has been demonstrated to dramatically increase the size of nanodiscs (up to similar to 60 nm diameter). Here, we report the first demonstration of the formation of macro-nanodiscs for a variety of lipids, and solid-state NMR experiments utilizing their magnetic-alignment properties.
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页码:10824 / 10826
页数:3
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