Generalized intramuscular granulocytic sarcoma mimicking polymyositis

被引：6
作者：
Fritz, Jan
Vogel, Wichard
Claussen, Claus D.
Wehrmann, Martin
Pereira, Philippe L.
Horger, Marius S.
机构：
[1] Univ Tubingen, Dept Diagnost Radiol, D-72076 Tubingen, Germany
[2] Univ Tubingen, Dept Internal Med Oncol, D-72070 Tubingen, Germany
[3] Univ Tubingen, Dept Pathol, D-72076 Tubingen, Germany
来源：
SKELETAL RADIOLOGY | 2007年 / 36卷 / 10期
关键词：
chloroma; granulocytic sarcoma; myelogenous leukemia; CT; MRI;
D O I：
10.1007/s00256-007-0314-6
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
We report a case of granulocytic sarcoma exclusively manifesting as diffuse intramuscular infiltration of the proximal upper and lower limb girdle and the torso muscles in a patient with previous history of acute myelogenous leukemia 5a. Whole-body CT showed widespread distribution of ill-defined intramuscular, homogeneously enhancing lesions. On whole-body MRI, lesions were homogeneously hyperintense on fat saturated T2-weighted images, isointense on T1-weighted images and strongly enhancing after intravenous gadolinium contrast administration. Histopathology revealed muscular infiltration of blast cells with identical immunochemistry to the initial manifestation of leukemia, diagnostic for an extramedullary relapse manifesting as granulocytic sarcoma. CT and MRI characteristics of this previously undocumented manifestation of granulocytic sarcoma should assist in the identification of such cases.
引用
收藏
页码：985 / 989
页数：5
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