Clinical relevance of human papillomavirus testing in cytopathology

被引：34

作者：

Brink, AATP ^{[1
]}

Zielinski, GD ^{[1
]}

Steenbergen, RDM ^{[1
]}

Snijders, PJF ^{[1
]}

Meijer, CJLM ^{[1
]}

机构：

[1] Vrije Univ Amsterdam, Ctr Med, Dept Pathol, NL-1081 HV Amsterdam, Netherlands

来源：

CYTOPATHOLOGY | 2005年 / 16卷 / 01期

关键词：

human papillomavirus; cervical carcinoma; cervical intraepithelial neoplasia; cytology; screening;

D O I：

10.1111/j.1365-2303.2004.00227.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Cancer of the uterine cervix is the second most common cancer in women worldwide. Currently, cervical screening is based on cytology alone. Because infection with high-risk human papillomavirus types (hrHPVs) is a necessary cause of cervical cancer, it has been postulated that screening might become more efficient when it is based on combined cytology and hrHPV testing. In this review we will discuss the advantages of added HPV tests in cervical cancer screening, as a quality control for false-negative smears, in triage of women with equivocal smears, in follow-up of women treated for CIN3 or cervical cancer and for the detection of cervical adenocarcinoma.

引用

页码：7 / 12

页数：6

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