Continuous intrathecal baclofen therapy in children with cerebral palsy - when does improvement emerge?

被引：28

作者：

Ramstad, K. ^{[1
]}

Jahnsen, R.

Lofterod, B.

Skjeldal, O. H. ^{[2
]}

机构：

[1] Oslo Univ Hosp, Dept Paediat, Rikshosp, N-0027 Oslo, Norway

[2] Innlandet Hosp Trust, Dept Res, Brumunddal, Norway

来源：

ACTA PAEDIATRICA | 2010年 / 99卷 / 11期

关键词：

Cerebral palsy; Child; Therapy; GROSS MOTOR FUNCTION; QUALITY-OF-LIFE; SPASTICITY; RELIABILITY; EFFICACY; DISABILITY; DYSTONIA; VALIDITY; SAFETY; PARENT;

D O I：

10.1111/j.1651-2227.2009.01596.x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Aim: The aim of the study was to explore the timing of effects of intrathecal baclofen therapy in children with cerebral palsy. Methods: Thirty five children with severe disabilities with cerebral palsy who started continuous intrathecal baclofen therapy (CITB) were followed for 18 months. Pain, number of awakenings during night, spasticity, GMFM-66 scores and PEDI scores were recorded the day before pump implantation and after 6 and 18 months of treatment respectively. Results: Introduction of CITB was associated with changes across all ICF dimensions. Reduced pain and improved sleep occurred within 6 months of treatment. Social function improved within 6 months and continued to improve until 18 months of CITB. Mobility also improved, but with a latency. Conclusion: There seems to be a sequence of changes after introduction of continuous intrathecal baclofen in a child with cerebral palsy that may guide the multidisciplinary team in their timing of therapy during post-surgical follow-up.

引用

页码：1661 / 1665

页数：5

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