This thesis used the pyrene-based pressure sensitive paints as the experimental object, fluorescence characteristics were measured by fluorophotometer, fluorescence characteristics and oxygen quenching coefficient were studied on different concentrations of pressure sensitive paints. The results showed that the fluorescence intensity in Monomer Emission(ME) was radually weakened with the increase of the concentration of pyrene in paint, but the fluorescence intensity in Excimer Emission(EE) was gradually increased. Oxygen quenching coefficient is low in the pyrene-based paints, it can reach its highest value at 20% when the concentration of pyrene in paint is 30mM.