Use-dependent corticospinal excitability is associated with resilience and physical performance during simulated military operational stress

被引：2

作者：

Proessl, F. ^{[1
]}

Canino, M. C. ^{[1
]}

Beckner, M. E. ^{[1
]}

Conkright, W. R. ^{[1
]}

LaGoy, A. D. ^{[1
]}

Sinnott, A. M. ^{[1
]}

Eagle, S. R. ^{[1
]}

Martin, B. J. ^{[1
]}

Sterczala, A. J. ^{[1
]}

Roma, P. G. ^{[2
]}

Dretsch, M. N. ^{[3
]}

Mi, Qi ^{[1
]}

Ferrarelli, F. ^{[4
]}

Germain, A. ^{[4
]}

Connaboy, C. ^{[1
]}

Nindl, B. C. ^{[1
]}

Flanagan, S. D. ^{[1
]}

机构：

[1] Univ Pittsburgh, Neuromuscular Res Lab, Warrior Human Performance Res Ctr, Dept Sports Med & Nutr, Pittsburgh, PA 15260 USA

[2] NASA Johnson Space Ctr KBR, Behav Hlth & Performance Lab, Biomed Res & Environm Sci Div, Human Hlth & Performance Directorate, Houston, TX USA

[3] Walter Reed Army Inst Res, US Army Med Res Directorate West, Joint Base Lewis McChord, Washington, DC USA

[4] Univ Pittsburgh, Sch Med, Dept Psychiat, Pittsburgh, PA 15260 USA

来源：

JOURNAL OF APPLIED PHYSIOLOGY | 2022年 / 132卷 / 01期

基金：

美国国家航空航天局;

关键词：

motor cortex; physical activity; resilience; transcranial magnetic stimulation; use-dependent plasticity; TRANSCRANIAL MAGNETIC STIMULATION; MOTOR CORTICAL OUTPUTS; NEUROTROPHIC FACTOR; READING HAND; PLASTICITY; BRAIN; EXERCISE; MODULATION; RESPONSES; CORTISOL;

D O I：

10.1152/japplphysiol.00628.2021

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Simulated military operational stress (SMOS) provides a useful model to better understand resilience in humans as the stress associated with caloric restriction, sleep deficits, and fatiguing exertion degrades physical and cognitive performance. Habitual physical activity may confer resilience against these stressors by promoting favorable use-dependent neuroplasticity, but it is unclear how physical activity, resilience, and corticospinal excitability (CSE) relate during SMOS. To examine associations between corticospinal excitability, physical activity, and physical performance during SMOS. Fifty-three service members (age: 26 +/- 5 yr, 13 women) completed a 5-day and -night intervention composed of familiarization, baseline, SMOS (2 nights/days), and recovery days. During SMOS, participants performed rigorous physical and cognitive activities while receiving half of normal sleep (two 2-h blocks) and caloric requirements. Lower and upper limb CSE were determined with transcranial magnetic stimulation (TMS) stimulus-response curves. Self-reported resilience, physical activity, military-specific physical performance (TMT), and endocrine factors were compared in individuals with high (HIGH) and low CSE based on a median split of lower limb CSE at baseline. HIGH had greater physical activity and better TMT performance throughout SMOS. Both groups maintained physical performance despite substantial psychophysiological stress. Physical activity, resilience, and TMT performance were directly associated with lower limb CSE. Individual differences in physical activity coincide with lower (but not upper) limb CSE. Such use-dependent corticospinal excitability directly relates to resilience and physical performance during SMOS. Future studies may use noninvasive neuromodulation to clarify the interplay among CSE, physical activity, and resilience and improve physical and cognitive performance. NEW & NOTEWORTHY We demonstrate that individual differences in physical activity levels coincide with lower limb corticospinal excitability. Such use-dependent corticospinal excitability directly relates to resilience and physical performance during a 5-day simulation of military operational stress with caloric restriction, sleep restriction and disruption, and heavy physical and cognitive exertion.

引用

页码：187 / 198

页数：12

共 74 条

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