Diagnostic work-up for severe aplastic anemia in children: Consensus of the North American Pediatric Aplastic Anemia Consortium

被引：24

作者：

Shimano, Kristin A. ^{[1
]}

Narla, Anupama ^{[2
]}

Rose, Melissa J. ^{[3
]}

Gloude, Nicholas J. ^{[4
]}

Allen, Steven W. ^{[5
]}

Bergstrom, Katie ^{[6
]}

Broglie, Larisa ^{[7
]}

Carella, Beth A. ^{[8
]}

Castillo, Paul ^{[9
]}

de Jong, Jill L. O. ^{[10
]}

Dror, Yigal ^{[11
]}

Geddis, Amy E. ^{[6
]}

Huang, James N. ^{[1
]}

Lau, Bonnie W. ^{[12
]}

McGuinn, Catherine ^{[13
]}

Nakano, Taizo A. ^{[14
]}

Overholt, Kathleen ^{[15
]}

Rothman, Jennifer A. ^{[16
]}

Sharathkumar, Anjali ^{[17
]}

Shereck, Evan ^{[18
]}

Vlachos, Adrianna ^{[19
]}

Olson, Timothy S. ^{[20
,21
]}

Bertuch, Alison A. ^{[22
]}

Wlodarski, Marcin W. ^{[23
]}

Shimamura, Akiko ^{[24
,25
]}

Boklan, Jessica ^{[26
]}

机构：

[1] Univ Calif San Francisco, Dept Pediat, Benioff Childrens Hosp, San Francisco, CA USA

[2] Stanford Univ, Dept Pediat, Sch Med, Stanford, CA 94305 USA

[3] Ohio State Univ, Coll Med, Nationwide Childrens Hosp, Div Hematol Oncol & Bone Marrow Transplant, Columbus, OH 43210 USA

[4] Univ Calif San Diego, Dept Pediat, Rady Childrens Hosp, San Diego, CA 92103 USA

[5] Univ Pittsburgh, UPMC Childrens Hosp Pittsburgh, Pediat Hematol Oncol, Sch Med, Pittsburgh, PA USA

[6] Seattle Childrens Hosp, Canc & Blood Disorders Ctr, Washington, DC USA

[7] Med Coll Wisconsin, Dept Pediat Hematol Oncol Blood & Marrow Transpla, Milwaukee, WI 53226 USA

[8] Kaiser Permanente, Dept Pediat, Washington, DC USA

[9] UF Hlth Shands Childrens Hosp, Div Pediat Hematol Oncol, Gainesville, FL USA

[10] Univ Chicago, Dept Pediat, Sect Hematol Oncol, Chicago, IL 60637 USA

[11] Hosp Sick Children, Dept Paediat, Marrow Failure & Myelodysplasia Program, Div Hematol & Oncol, Toronto, ON, Canada

[12] Dartmouth Hitchcock, Pediat Hematol Oncol, Lebanon, NH USA

[13] Weill Cornell Med, Dept Pediat, New York, NY USA

[14] Childrens Hosp Colorado, Ctr Canc & Blood Disorders, Aurora, CO USA

[15] Indiana Univ, Riley Hosp Children, Pediat Hematol & Oncol, Indianapolis, IN 46204 USA

[16] Duke Univ, Med Ctr, Div Pediat Hematol & Oncol, Durham, NC USA

[17] Univ Iowa, Carver Coll Med, Stead Family Dept Pediat, Iowa City, IA USA

[18] Oregon Hlth & Sci Univ, Dept Pediat, 3181 Sw Sam Jackson Pk Rd, Portland, OR 97201 USA

[19] Cohen Childrens Med Ctr, Hematol Oncol & Cellular Therapy, New Hyde Pk, NY USA

[20] Childrens Hosp Philadelphia, Dept Pediat, Cell Therapy & Transplant Sect, Div Oncol & Bone Marrow Failure,Div Hematol, Philadelphia, PA 19104 USA

[21] Univ Penn, Philadelphia, PA 19104 USA

[22] Baylor Coll Med, Pediat, Houston, TX 77030 USA

[23] St Jude Childrens Res Hosp, Dept Hematol, Memphis, TN USA

[24] Boston Childrens Hosp, Canc & Blood Disorders Ctr, Boston, MA USA

[25] Dana Farber Canc Inst, Boston, MA 02115 USA

[26] Phoenix Childrens Hosp, Ctr Canc & Blood Disorders, Phoenix, AZ 85016 USA

来源：

AMERICAN JOURNAL OF HEMATOLOGY | 2021年 / 96卷 / 11期

关键词：

PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA; BONE-MARROW-TRANSPLANTATION; SHWACHMAN-DIAMOND-SYNDROME; GPI-DEFICIENT CELLS; TELOMERE LENGTH; FETAL-HEMOGLOBIN; IMMUNOSUPPRESSIVE THERAPY; REFRACTORY CYTOPENIA; FANCONI-ANEMIA; MYELODYSPLASTIC SYNDROMES;

D O I：

10.1002/ajh.26310

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The North American Pediatric Aplastic Anemia Consortium (NAPAAC) is a group of pediatric hematologist-oncologists, hematopathologists, and bone marrow transplant physicians from 46 institutions in North America with interest and expertise in aplastic anemia, inherited bone marrow failure syndromes, and myelodysplastic syndromes. The NAPAAC Bone Marrow Failure Diagnosis and Care Guidelines Working Group was established with the charge of harmonizing the approach to the diagnostic workup of aplastic anemia in an effort to standardize best practices in the field. This document outlines the rationale for initial evaluations in pediatric patients presenting with signs and symptoms concerning for severe aplastic anemia.

引用

页码：1491 / 1504

页数：14

共 109 条

[1] International recommendations for the assessment of autoantibodies to cellular antigens referred to as anti-nuclear antibodies
Agmon-Levin, Nancy
Damoiseaux, Jan
Kallenberg, Cees
Sack, Ulrich
Witte, Torsten
Herold, Manfred
Bossuyt, Xavier
Musset, Lucille
Cervera, Ricard
Plaza-Lopez, Aresio
Dias, Carlos
Sousa, Maria Jose
Radice, Antonella
Eriksson, Catharina
Hultgren, Olof
Viander, Markku
Khamashta, Munther
Regenass, Stephan
Coelho Andrade, Luis Eduardo
Wiik, Allan
Tincani, Angela
Ronnelid, Johan
Bloch, Donald B.
Fritzler, Marvin J.
Chan, Edward K. L.
Garcia-De la Torre, I.
Konstantinov, Konstantin N.
Lahita, Robert
Wilson, Merlin
Vainio, Olli
Fabien, Nicole
Sinico, Renato Alberto
Meroni, Pierluigi
Shoenfeld, Yehuda
[J]. ANNALS OF THE RHEUMATIC DISEASES, 2014, 73 (01) : 17 - 23
[2] Diagnostic utility of telomere length testing in a hospital-based setting
Alder, Jonathan K.
Hanumanthu, Vidya Sagar
Strong, Margaret A.
DeZern, Amy E.
Stanley, Susan E.
Takemoto, Clifford M.
Danilova, Ludmilla
Applegate, Carolyn D.
Bolton, Stephen G.
Mohr, David W.
Brodsky, Robert A.
Casella, James F.
Greider, Carol W.
Jackson, J. Brooks
Armanios, Mary
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 115 (10) : E2358 - E2365
[3] Very short telomere length by flow fluorescence in situ hybridization identifies patients with dyskeratosis congenita
Alter, Blanche P.
Baerlocher, Gabriela M.
Savage, Sharon A.
Chanock, Stephen J.
Weksler, Babette B.
Willner, Judith P.
Peters, June A.
Giri, Neelarn
Lansdorp, Peter M.
[J]. BLOOD, 2007, 110 (05) : 1439 - 1447
[4] Inherited bone marrow failure syndromes: considerations pre- and posttransplant
Alter, Blanche P.
[J]. BLOOD, 2017, 130 (21) : 2257 - 2264
[5] Genetic regulation of fetal haemoglobin in inherited bone marrow failure syndromes
Alter, Blanche P.
Rosenberg, Philip S.
Day, Thomas
Menzel, Stephan
Giri, Neelam
Savage, Sharon A.
Thein, Swee Lay
[J]. BRITISH JOURNAL OF HAEMATOLOGY, 2013, 162 (04) : 542 - 546
[6] Telomere length is associated with disease severity and declines with age in dyskeratosis congenita
Alter, Blanche P.
Rosenberg, Philip S.
Giri, Neelam
Baerlocher, Gabriela M.
Lansdorp, Peter M.
Savage, Sharon A.
[J]. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2012, 97 (03): : 353 - 359
[7] ALTER BP, 1979, EXP HEMATOL, V7, P200
[8] Aringer M, 2019, ARTHRITIS RHEUMATOL, V71, P1400, DOI [10.1002/art.40930, 10.1136/annrheumdis-2018-214819]
[9] Auerbach Arleen D, 2015, Curr Protoc Hum Genet, V85, DOI 10.1002/0471142905.hg0807s85
[10] Fanconi anemia and its diagnosis
Auerbach, Arleen D.
[J]. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2009, 668 (1-2) : 4 - 10

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