Diagnosis and Management of Coccidioidomycosis

被引:41
作者
Gabe, Luke M. [1 ]
Malo, Joshua [1 ]
Knox, Kenneth S. [1 ]
机构
[1] Univ Arizona, Coll Med Tucson, Div Pulm Allergy Crit Care & Sleep Med, 1501 North Campbell Ave, Tucson, AZ 85724 USA
关键词
Coccidioidomycosis; Fungal infections; Diagnosis; Treatment; DELAYED-TYPE HYPERSENSITIVITY; PULMONARY COCCIDIOIDOMYCOSIS; SYMPTOMATIC COCCIDIOIDOMYCOSIS; BLASTOMYCES-DERMATITIDIS; EOSINOPHILIC PNEUMONIA; RENAL-TRANSPLANTATION; ENZYME-IMMUNOASSAY; IMMITIS FUNGEMIA; UNITED-STATES; RISK;
D O I
10.1016/j.ccm.2017.04.005
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Coccidioidomycosis is a leading cause of community-acquired pneumonia within its traditional endemic zone in the Southwestern United States and portions of Mexico and Central and South America. Its incidence has increased dramatically within the endemic region; its presence outside of the region, facilitated by a mobile society, is also now substantial. Although only a fraction of the incident disease progresses beyond subclinical illness, this proportion is large in absolute terms and causes substantial disease burden. Diagnosis often depends on serologic interpretation. Treatment has been revolutionized by azole therapy. Controversy remains regarding the decision to treat in less severe disease..
引用
收藏
页码:417 / +
页数:19
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