DDQ-Mediated Cross-Dehydrogenative-Coupling Reaction of Secondary Amines with Dialkyl Phosphonates

被引：7

作者：

Cheng, Ming-Xing ^{[1
]}

Lei, Jing-Wei ^{[1
]}

Xie, Cai-Xia ^{[1
]}

机构：

[1] Henan Univ Chinese Med, Coll Pharm, 156 Jinshui East Rd, Zhengzhou 450046, Henan, Peoples R China

来源：

SYNLETT | 2019年 / 30卷 / 01期

关键词：

DDQ; cross-dehydrogenative-coupling; phosphonylation; allylic amines; dialkyl phosphonates; aminophosphonates; OXIDATIVE C-C; ALPHA-AMINOPHOSPHONATES; BIOLOGICAL-PROPERTIES; ACID; PHOSPHONYLATION; PHOSPHONOPEPTIDES; INHIBITORS; STRATEGY; BINDING; ESTERS;

D O I：

10.1055/s-0037-1611362

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This work reports a DDQ-mediated cross-dehydrogenative-coupling reaction of secondary amines with dialkyl phosphonates under mild conditions. This reaction proceeds efficiently without involving visible light or transition-metal catalysis. This new approach provides efficient access to biologically important -aminophosphonates.

引用

收藏

页码：114 / 118

页数：5

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