DDQ-Mediated Cross-Dehydrogenative-Coupling Reaction of Secondary Amines with Dialkyl Phosphonates

被引：7
|
作者：
Cheng, Ming-Xing [1 ]
Lei, Jing-Wei [1 ]
Xie, Cai-Xia [1 ]
机构：
[1] Henan Univ Chinese Med, Coll Pharm, 156 Jinshui East Rd, Zhengzhou 450046, Henan, Peoples R China
来源：
SYNLETT | 2019年 / 30卷 / 01期
关键词：
DDQ; cross-dehydrogenative-coupling; phosphonylation; allylic amines; dialkyl phosphonates; aminophosphonates; OXIDATIVE C-C; ALPHA-AMINOPHOSPHONATES; BIOLOGICAL-PROPERTIES; ACID; PHOSPHONYLATION; PHOSPHONOPEPTIDES; INHIBITORS; STRATEGY; BINDING; ESTERS;
D O I：
10.1055/s-0037-1611362
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
This work reports a DDQ-mediated cross-dehydrogenative-coupling reaction of secondary amines with dialkyl phosphonates under mild conditions. This reaction proceeds efficiently without involving visible light or transition-metal catalysis. This new approach provides efficient access to biologically important -aminophosphonates.
引用
收藏
页码：114 / 118
页数：5
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