Does C-Reactive Protein Predict Recurrent Preeclampsia?

Objective Evaluate association of the inflammatory marker C reactive protein with recurrent preeclampsia Methods Serum samples collected longitudinally in women with previous preeclampsia from the Maternal Fetal Medicine Units Network trial of aspirin to prevent preeclampsia were assayed for CRP Results Of 255 women studied, 50 developed recurrence Baseline C reactive protein concentration was similar between women who did and did not recur After adjusting for confounders, neither elevated baseline C reactive protein nor its change over gestation was associated with recurrence Conclusion In this group of women with previous preeclampsia, neither baseline C reactive protein concentration nor change in concentration over gestation was associated with recurrent preeclampsia