Nickel-catalyzed C(sp2)-H selenation of imidazo[1,2-α]pyridines with arylboronic acids or alkyl reagents using selenium powder

被引：26

作者：

Zhu, Jie ^{[1
]}

Zhu, Wenhui ^{[1
]}

Xie, Ping ^{[2
]}

Pittman, Charles U., Jr. ^{[3
]}

Zhou, Aihua ^{[1
]}

机构：

[1] Jiangsu Univ, Pharm Sch, Xuefu Rd 301, Zhenjiang City 212013, Jiangsu, Peoples R China

[2] Jiangsu Univ Lib, Xuefu Rd 301, Zhenjiang City 212013, Jiangsu, Peoples R China

[3] Mississippi State Univ, Dept Chem, Mississippi State, MS 39762 USA

来源：

TETRAHEDRON | 2018年 / 74卷 / 45期

关键词：

Selenium; C-Se bond; Nickel-catalyzed; C-H functionalization; Arylboronic acid; S BOND FORMATION; ELEMENTAL SULFUR; ANTIOXIDANT ACTIVITY; PEROXIDASE-ACTIVITY; POTENT ACTIVITY; DISELENIDES; ARYL; ORGANOSELENIUM; CHALCOGENATION; SOLVENT;

D O I：

10.1016/j.tet.2018.09.037

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and efficient Ni-catalyzed aryl- and alkyl-selenation of imidazo[1,2-alpha]pyridines employing selenium powder has been developed for the first time. The significant advantages of this protocol are that it is an inexpensive nickel catalyst and exhibits broad functional-group compatibility and good reaction yields. (C) 2018 Published by Elsevier Ltd.

引用

页码：6569 / 6576

页数：8

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