Conjugated polyelectrolytes for label-free visual detection of heparin

被引：21

作者：

Pu KanYi ^{[1
]}

Zhan RuoYu ^{[1
]}

Liang Jing ^{[1
]}

Liu Bin ^{[1
]}

机构：

[1] Natl Univ Singapore, Dept Chem & Biomol Engn, Singapore 117576, Singapore

来源：

SCIENCE CHINA-CHEMISTRY | 2011年 / 54卷 / 04期

关键词：

conjugated polyelectrolyte; heparin; fluorescence resonance energy transfer; sensor; SINGLE-STRANDED-DNA; ENERGY-TRANSFER; FLUORESCENT SENSORS; OPTICAL-DETECTION; CHARGE-TRANSFER; POLYMERS; PROBES; POLYTHIOPHENES; AMPLIFICATION; COMPLEXES;

D O I：

10.1007/s11426-011-4241-y

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Conjugated polyelectrolytes (CPEs), with electron-delocalized backbones and charged ionic side chains, are unique sensory materials for the construction of optical biosensors. In this feature article, CPE-based visual detection of heparin is summarized. Three CPE-based heparin probes, including ratiometric, light-up and colormetric probes, are discussed in terms of molecular design, detection selectivity and quantification capability. The work summarized here provides fundamental guidelines for CPE-based label-free visual sensing.

引用

页码：567 / 574

页数：8

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