Conjugated polyelectrolytes for label-free visual detection of heparin

被引：21
|
作者：
Pu KanYi [1 ]
Zhan RuoYu [1 ]
Liang Jing [1 ]
Liu Bin [1 ]
机构：
[1] Natl Univ Singapore, Dept Chem & Biomol Engn, Singapore 117576, Singapore
来源：
SCIENCE CHINA-CHEMISTRY | 2011年 / 54卷 / 04期
关键词：
conjugated polyelectrolyte; heparin; fluorescence resonance energy transfer; sensor; SINGLE-STRANDED-DNA; ENERGY-TRANSFER; FLUORESCENT SENSORS; OPTICAL-DETECTION; CHARGE-TRANSFER; POLYMERS; PROBES; POLYTHIOPHENES; AMPLIFICATION; COMPLEXES;
D O I：
10.1007/s11426-011-4241-y
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Conjugated polyelectrolytes (CPEs), with electron-delocalized backbones and charged ionic side chains, are unique sensory materials for the construction of optical biosensors. In this feature article, CPE-based visual detection of heparin is summarized. Three CPE-based heparin probes, including ratiometric, light-up and colormetric probes, are discussed in terms of molecular design, detection selectivity and quantification capability. The work summarized here provides fundamental guidelines for CPE-based label-free visual sensing.
引用
收藏
页码：567 / 574
页数：8
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