Total serum bilirubin and risk of cardiovascular disease in the Framingham Offspring Study

被引：249
作者：
Djoussé, L
Levy, D
Cupples, LA
Evans, JC
D'Agostino, RB
Ellison, RC
机构：
[1] NHLBI, Framingham Heart Study, Framingham, MA USA
[2] Boston Univ, Sch Publ Hlth, Dept Biostat & Epidemiol, Boston, MA 02118 USA
[3] Boston Univ, Dept Math, Boston, MA 02118 USA
来源：
AMERICAN JOURNAL OF CARDIOLOGY | 2001年 / 87卷 / 10期
关键词：
D O I：
10.1016/S0002-9149(01)01494-1
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The association between bilirubin and cardiovascular disease is controversial. In a prospective study of 4.276 subjects, we demonstrated that a higher concentration of serum bilirubin was associated with lower risk of myocardial infarction and cardiovascular disease in men, but the pattern was not clear in women.
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收藏
页码：1196 / +
页数：6
相关论文
共 19 条
  • [11] BILIRUBIN ATTENUATES RADICAL-MEDIATED DAMAGE TO SERUM-ALBUMIN
    NEUZIL, J
    STOCKER, R
    [J]. FEBS LETTERS, 1993, 331 (03) : 281 - 284
  • [12] VITAMIN-E CONSUMPTION AND THE RISK OF CORONARY HEART-DISEASE IN MEN
    RIMM, EB
    STAMPFER, MJ
    ASCHERIO, A
    GIOVANNUCCI, E
    COLDITZ, GA
    WILLETT, WC
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1993, 328 (20) : 1450 - 1456
  • [13] SCHWERTNER HA, 1994, CLIN CHEM, V40, P18
  • [14] STOCKER R, 1990, METHOD ENZYMOL, V186, P301
  • [15] BILIRUBIN IS AN ANTIOXIDANT OF POSSIBLE PHYSIOLOGICAL IMPORTANCE
    STOCKER, R
    YAMAMOTO, Y
    MCDONAGH, AF
    GLAZER, AN
    AMES, BN
    [J]. SCIENCE, 1987, 235 (4792) : 1043 - 1046
  • [16] UNCONJUGATED BILIRUBIN INHIBITS THE OXIDATION OF HUMAN LOW-DENSITY-LIPOPROTEIN BETTER THAN TROLOX
    WU, TW
    FUNG, KP
    YANG, CC
    [J]. LIFE SCIENCES, 1994, 54 (25) : PL477 - PL481
  • [17] Antioxidation of human low density lipoprotein by unconjugated and conjugated bilirubins
    Wu, TW
    Fung, KP
    Wu, J
    Yang, CC
    Weisel, RD
    [J]. BIOCHEMICAL PHARMACOLOGY, 1996, 51 (06) : 859 - 862
  • [18] THE CYTOPROTECTIVE EFFECTS OF BILIRUBIN AND BILIVERDIN ON RAT HEPATOCYTES AND HUMAN ERYTHROCYTES AND THE IMPACT OF ALBUMIN
    WU, TW
    CAREY, D
    WU, J
    SUGIYAMA, H
    [J]. BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE, 1991, 69 (12): : 828 - 834
  • [19] ALBUMIN-BOUND BILIRUBINS PROTECT HUMAN VENTRICULAR MYOCYTES AGAINST OXYRADICAL DAMAGE
    WU, TW
    WU, J
    LI, RK
    MICKLE, D
    CAREY, D
    [J]. BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE, 1991, 69 (10-11): : 683 - 688
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