DNA vs cDNA FLT3-ITD allelic ratio and length measurements in adult acute myeloid leukemia

被引：4

作者：

Cucchi, David G. J. ^{[1
]}

Vonk, Christian M. ^{[2
]}

Rijken, Melissa ^{[2
]}

Kavelaars, Francois G. ^{[2
]}

Merle, Pauline A. ^{[1
]}

Verhoef, Elvira ^{[1
]}

Venniker-Punt, Bianca ^{[1
]}

Kwidama, Zinia J. ^{[1
]}

Gradowska, Patrycja ^{[2
]}

Lowenberg, Bob ^{[2
]}

Janssen, Jeroen J. W. M. ^{[1
]}

Cloos, Jacqueline ^{[1
]}

Valk, Peter J. M. ^{[2
]}

机构：

[1] Vrije Univ Amsterdam, Amsterdam Univ Med Ctr, Canc Ctr Amsterdam, Dept Hematol, Amsterdam, Netherlands

[2] Univ Med Ctr Rotterdam, Erasmus Med Ctr, Inst Canc, Dept Hematol, Rotterdam, Netherlands

来源：

BLOOD ADVANCES | 2021年 / 5卷 / 21期

关键词：

INTERNAL TANDEM DUPLICATION; PROGNOSTIC-SIGNIFICANCE; SIZE; CHEMOTHERAPY; MUTATIONS; IMPACT;

D O I：

10.1182/bloodadvances.2021004980

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：4476 / 4479

页数：4

共 15 条

[1] Two decades of targeted therapies in acute myeloid leukemia [J].

Cucchi, David G. J. ;

Polak, Tobias B. ;

Ossenkoppele, Gert J. ;

Uyl-De Groot, Carin A. ;

Cloos, Jacqueline ;

Zweegman, Sonja ;

Janssen, Jeroen J. W. M. .

LEUKEMIA, 2021, 35 (03) :651-660

[2] RNA-based FLT3-ITD allelic ratio is associated with outcome and ex vivo response to FLT3 inhibitors in pediatric AML [J].

Cucchi, David G. J. ;

Denys, Barbara ;

Kaspers, Gertjan J. L. ;

Janssen, Jeroen J. W. M. ;

Ossenkoppele, Gert J. ;

de Haas, Valerie ;

Zwaan, C. Michel ;

van den Heuvel-Eibrink, Marry M. ;

Philippe, Jan ;

Csikos, Tamas ;

Kwidama, Zinia ;

de Moerloose, Barbara ;

de Bont, Eveline S. J. M. ;

Lissenberg-Witte, Birgit I. ;

Zweegman, Sonja ;

Verwer, Femke ;

Vandepoele, Karl ;

Schuurhuis, Gerrit Jan ;

Sonneveld, Edwin ;

Cloos, Jacqueline .

BLOOD, 2018, 131 (22) :2485-2489

[3] Impact of numerical variation, allele burden, mutation length and co-occurring mutations on the efficacy of tyrosine kinase inhibitors in newly diagnosed FLT3-mutant acute myeloid leukemia [J].

Dalle, Iman Abou ;

Ghorab, Ahmad ;

Patel, Keyur ;

Wang, Xuemei ;

Hwang, Hyunsoo ;

Cortes, Jorge ;

Issa, Ghayas C. ;

Yalniz, Fevzi ;

Sasaki, Koji ;

Chihara, Dai ;

Price, Allyson ;

Kadia, Tapan ;

Pemmaraju, Naveen ;

Daver, Naval ;

DiNardo, Courtney ;

Ravandi, Farhad ;

Kantarjian, Hagop M. ;

Borthakur, Gautam .

BLOOD CANCER JOURNAL, 2020, 10 (05)

[4]

Deeb Kristin K, 2014, Leuk Res Rep, V3, P86, DOI 10.1016/j.lrr.2013.09.003

[5] Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel [J].

Doehner, Hartmut ;

Estey, Elihu ;

Grimwade, David ;

Amadori, Sergio ;

Appelbaum, Frederick R. ;

Buechner, Thomas ;

Dombret, Herve ;

Ebert, Benjamin L. ;

Fenaux, Pierre ;

Larson, Richard A. ;

Levine, Ross L. ;

Lo-Coco, Francesco ;

Naoe, Tomoki ;

Niederwieser, Dietger ;

Ossenkoppele, Gert J. ;

Sanz, Miguel ;

Sierra, Jorge ;

Tallman, Martin S. ;

Tien, Hwei-Fang ;

Wei, Andrew H. ;

Lowenberg, Bob ;

Bloomfield, Clara D. .

BLOOD, 2017, 129 (04) :424-447

[6] The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia [J].

Gale, Rosemary E. ;

Green, Claire ;

Allen, Christopher ;

Mead, Adam J. ;

Burnett, Alan K. ;

Hils, Robert K. ;

Linch, David C. .

BLOOD, 2008, 111 (05) :2776-2784

[7] More on prognostic significance of FLT3/ITD size in acute myeloid leukemia (AML) [J].

Kusec, Rajko ;

Jaksic, Ozren ;

Ostojic, Slobodanka ;

Kardum-Skelin, Ika ;

Vrhovac, Radovan ;

Jaksic, Branimir .

BLOOD, 2006, 108 (01) :405-406

[8] Impact of FLT3-ITD length on prognosis of acute myeloid leukemia [J].

Liu, Song-Bai ;

Dong, Hao-Jie ;

Bao, Xie-Bing ;

Qiu, Qiao-Cheng ;

Li, Hong-Zhi ;

Shen, Hong-Jie ;

Ding, Zi-Xuan ;

Wang, Chao ;

Chu, Xiao-Ling ;

Yu, Jing-Qiu ;

Tao, Tao ;

Li, Zheng ;

Tang, Xiao-Wen ;

Chen, Su-Ning ;

Wu, De-Pei ;

Li, Ling ;

Xue, Sheng-Li .

HAEMATOLOGICA, 2019, 104 (01) :E9-E12

[9] Addition of lenalidomide to intensive treatment in younger and middle-aged adults with newly diagnosed AML: the HOVON-SAKK-132 trial [J].

Lowenberg, Bob ;

Pabst, Thomas ;

Maertens, Johan ;

Gradowska, Patrycja ;

Biemond, Bart J. ;

Spertini, Olivier ;

Vellenga, Edo ;

Griskevicius, Laimonas ;

Tick, Lidwine W. ;

Jongen-Lavrencic, Mojca ;

Kooy, Marinus van Marwijk ;

Vekemans, Marie-Christiane ;

van der Velden, Walter J. F. M. ;

Beverloo, Berna ;

Michaux, Lucienne ;

Graux, Carlos ;

Deeren, Dries ;

de Weerdt, Okke ;

van Esser, Joost W. J. ;

Bargetzi, Mario ;

Klein, Saskia K. ;

Gadisseur, Alain ;

Westerweel, Peter E. ;

Veelken, Hendrik ;

Gregor, Michael ;

Silzle, Tobias ;

Van Lammeren-Venema, Danielle ;

Moors, Ine ;

Breems, Dimitri A. ;

Hoogendoorn, Mels ;

Legdeur, Marie-Cecile J. C. ;

Fischer, Thomas ;

Kuball, Juergen ;

Cornelissen, Jan ;

Porkka, Kimmo ;

Juliusson, Gunnar ;

Meyer, Peter ;

Hoglund, Martin ;

Gjertsen, Bjorn T. ;

Janssen, Jeroen J. W. M. ;

Huls, Gerwin ;

Passweg, Jakob ;

Cloos, Jacqueline ;

Valk, Peter J. M. ;

van Elssen, Catharina H. M. J. ;

Manz, Markus G. ;

Floisand, Yngvar ;

Ossenkoppele, Gert J. .

BLOOD ADVANCES, 2021, 5 (04) :1110-1121

[10] Therapeutic value of clofarabine in younger and middle-aged (18-65 years) adults with newly diagnosed AML [J].

Lowenberg, Bob ;

Pabst, Thomas ;

Maertens, Johan ;

van Norden, Yvette ;

Biemond, Bart J. ;

Schouten, Harry C. ;

Spertini, Olivier ;

Vellenga, Edo ;

Graux, Carlos ;

Havelange, Violaine ;

de Greef, Georgine E. ;

de Weerdt, Okke ;

Legdeur, Marie-Cecile J. C. ;

Kuball, Juergen ;

Kooy, Marinus van Marwijk ;

Gjertsen, Bjorn T. ;

Jongen-Lavrencic, Mojca ;

de Loosdrecht, Arjan A. van ;

van Lammeren-Venema, Danielle ;

Hodossy, Beata ;

Breems, Dimitri A. ;

Chalandon, Yves ;

Passweg, Jakob ;

Valk, Peter J. M. ;

Manz, Markus G. ;

Ossenkoppele, Gert J. .

BLOOD, 2017, 129 (12) :1636-1645

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